N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

Base Information

Chemical Name:N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine
CAS No.:950773-10-1
Molecular Formula:C₂₁H₃₃N₃O₄
Molecular Weight:391.511
Hs Code.:

Synonyms:N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

Chemical Property:

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Technology Process of N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

There total 2 articles about N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-[trans-4-(methyloxy)-1-methylcyclohexyl]-4-piperidinamine dihydrochloride

: 28987-48-6
4-ethoxy-2-fluoro-1-nitrobenzene

: 950773-10-1
N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 200 ℃; for 0.333333h; Microwave reactor;

Reference yield:

: 394-41-2
3-fluoro-4-nitrophenol

: 950773-10-1
N-[5-(ethyloxy)-2-nitrophenyl]-1-[trans-1-methyl-4-(methyloxy)cyclohexyl]-4-piperidinamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / butanone / 2.5 h / 85 °C

2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.33 h / 200 °C / Microwave reactor

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; butanone;