2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde

Base Information

• Chemical Name: 2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde
• CAS No.: 1256723-56-4
• Molecular Formula: C₁₅H₂₄O₃Si
• Molecular Weight: 280.439
• Mol file: 1256723-56-4.mol

Synonyms:2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde

Chemical Property of 2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde

There total 1 articles about 2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(2-((tert-butyldimethylsilyloxy)methyl)-3-methoxyphenyl)methanol (1256723-55-3) → 2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde (1256723-56-4)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.08.068

Reference yield: 70.0%

2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde (1256723-56-4) + Methyltriphenylphosphonium bromide (1779-49-3) → tert-butyl(2-methoxy-6-vinylbenzyloxy)dimethylsilane (906102-60-1)

Guidance literature:

Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

2-((tert-butyldimethylsilyloxy)methyl)-3-methoxybenzaldehyde; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.08.068

upstream raw materials:

(2-((tert-butyldimethylsilyloxy)methyl)-3-methoxyphenyl)methanol

Downstream raw materials:

tert-butyl(2-methoxy-6-vinylbenzyloxy)dimethylsilane