Methyl 2-(2-bromo-1H-indol-3-yl)acetate

Base Information

Chemical Name:Methyl 2-(2-bromo-1H-indol-3-yl)acetate
CAS No.:1912-35-2
Molecular Formula:C11H10BrNO2
Molecular Weight:268.11
Hs Code.:2933990090
Mol file:1912-35-2.mol

Synonyms:Indole-3-aceticacid, 2-bromo-, methyl ester (7CI,8CI);1H-Indole-3-acetic acid, 2-bromo-, methyl ester;

Suppliers and Price of Methyl 2-(2-bromo-1H-indol-3-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2-BROMO-1H-INDOL-3-YL)-ACETIC ACID METHYL ESTER 95.00%
5G
$ 1334.03

Total 24 raw suppliers

Chemical Property of Methyl 2-(2-bromo-1H-indol-3-yl)acetate

Chemical Property:

Refractive Index:1.648
Boiling Point:394.1 °C at 760 mmHg
Flash Point:192.2 °C
PSA：42.09000
Density:1.569 g/cm³
LogP:2.64590

Purity/Quality:

97% ^*data from raw suppliers

(2-BROMO-1H-INDOL-3-YL)-ACETIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Methyl 2-(2-bromo-1H-indol-3-yl)acetate

There total 4 articles about Methyl 2-(2-bromo-1H-indol-3-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1912-33-0
Indole-3-acetic acid methyl ester

: 1912-35-2
methyl 2-(2-bromo-1H-indol-3-yl)acetate

Guidance literature:: With N-Bromosuccinimide; In tetrachloromethane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jo4013833

Reference yield:

: 87-51-4
indole-3-acetic acid

: 1912-35-2
methyl 2-(2-bromo-1H-indol-3-yl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; thionyl chloride; benzotriazol-1-ol / 4 h / 0 - 25 °C / Inert atmosphere

2: N-Bromosuccinimide; benzoic acid anhydride / tetrachloromethane / 2 h / 25 °C / Inert atmosphere

With hydrogenchloride; N-Bromosuccinimide; thionyl chloride; benzotriazol-1-ol; benzoic acid anhydride; In tetrachloromethane;
DOI:10.1039/c2ob06695e

Reference yield:

: 771-51-7
indole-3-acetonitrile

: 1912-35-2
methyl 2-(2-bromo-1H-indol-3-yl)acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: water; potassium hydroxide / methanol / 2 h / 100 °C / Inert atmosphere

1.2: 0 °C / pH 1 / Inert atmosphere

2.1: hydrogenchloride; thionyl chloride; benzotriazol-1-ol / 4 h / 0 - 25 °C / Inert atmosphere

3.1: N-Bromosuccinimide; benzoic acid anhydride / tetrachloromethane / 2 h / 25 °C / Inert atmosphere

With hydrogenchloride; N-Bromosuccinimide; thionyl chloride; water; benzotriazol-1-ol; benzoic acid anhydride; potassium hydroxide; In methanol; tetrachloromethane;
DOI:10.1039/c2ob06695e