5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Base Information

Chemical Name:5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole
CAS No.:1193384-86-9
Molecular Formula:C₁₉H₂₁ClN₂O₃
Molecular Weight:360.84
Hs Code.:

Synonyms:5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Suppliers and Price of 5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

There total 5 articles about 5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1193384-85-8
[2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazol-5-yl]-methanol

: 100-39-0
benzyl bromide

: 1193384-86-9
5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Guidance literature:: [2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazol-5-yl]-methanol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 1h;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; for 16h;

Reference yield:

: 106429-57-6
1,3-dihydro-2-oxo-2H-benzimidazole-5-carboxylic acid methyl ester

: 1193384-86-9
5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 4 steps

1.1: trichlorophosphate / 48 h / 100 °C

1.2: 0 - 23 °C

2.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 18 h / 23 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 48.17 h / 0 - 23 °C

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C

4.2: 16 h

With lithium aluminium tetrahydride; sodium hydride; N-ethyl-N,N-diisopropylamine; trichlorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 683242-75-3
methyl 2-chloro-1H-benzo[d]imidazole-5-carboxylate

: 1193384-86-9
5-benzyloxymethyl-2-chloro-1-(2-methoxy-ethoxymethyl)-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 18 h / 23 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 48.17 h / 0 - 23 °C

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 °C

3.2: 16 h

With lithium aluminium tetrahydride; sodium hydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;