Technology Process of 1,6-anhydro-2,3-di-O-benzyl-4-O-(2,3-di-O-benzyl-6-deoxy-α-D-galactopyranosyl)-β-D-glucopyranose
There total 8 articles about 1,6-anhydro-2,3-di-O-benzyl-4-O-(2,3-di-O-benzyl-6-deoxy-α-D-galactopyranosyl)-β-D-glucopyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) 0.42 M methanolic sodium methoxide; 2.) sodium hydride / 1.) methanol, r.t., overnight; 2.) DMF, r.t., 30 min; 3.) r.t., 3 h
2: 63 percent / water, acetic acid / 0.5 h / 97 - 98 °C
3: 74 percent / 1.) triphenylphosphine, N-iodosuccinimide / 1.) DMF, 50 deg C, 3 h; 2.) DMF, methanol, r.t., 1 h
4: 80 percent / lithium aluminium hydride / various solvent(s) / 2 h / Ambient temperature
5: 93 percent / pyridine; CH2Cl2 / 48 h / Ambient temperature
6: 1.) sodium benzoate; 2.) 2 M aqueous sodium hydroxide / 1.) hexamethylphosphoric triamide, 120-130 deg C, 16 h; 2.) methanol, r.t., overnight
With
sodium benzoate; sodium hydroxide; N-iodo-succinimide; lithium aluminium tetrahydride; water; sodium methylate; sodium hydride; acetic acid; triphenylphosphine;
In
pyridine; dichloromethane;
DOI:10.1016/0008-6215(83)88173-7
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) 0.42 M methanolic sodium methoxide; 2.) sodium hydride / 1.) methanol, r.t., overnight; 2.) DMF, r.t., 30 min; 3.) r.t., 3 h
2: 63 percent / water, acetic acid / 0.5 h / 97 - 98 °C
3: 74 percent / 1.) triphenylphosphine, N-iodosuccinimide / 1.) DMF, 50 deg C, 3 h; 2.) DMF, methanol, r.t., 1 h
4: 80 percent / lithium aluminium hydride / various solvent(s) / 2 h / Ambient temperature
5: 93 percent / pyridine; CH2Cl2 / 48 h / Ambient temperature
6: 1.) sodium benzoate; 2.) 2 M aqueous sodium hydroxide / 1.) hexamethylphosphoric triamide, 120-130 deg C, 16 h; 2.) methanol, r.t., overnight
With
sodium benzoate; sodium hydroxide; N-iodo-succinimide; lithium aluminium tetrahydride; water; sodium methylate; sodium hydride; acetic acid; triphenylphosphine;
In
pyridine; dichloromethane;
DOI:10.1016/0008-6215(83)88173-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 80 percent / lithium aluminium hydride / various solvent(s) / 2 h / Ambient temperature
2: 93 percent / pyridine; CH2Cl2 / 48 h / Ambient temperature
3: 1.) sodium benzoate; 2.) 2 M aqueous sodium hydroxide / 1.) hexamethylphosphoric triamide, 120-130 deg C, 16 h; 2.) methanol, r.t., overnight
With
sodium benzoate; sodium hydroxide; lithium aluminium tetrahydride;
In
pyridine; dichloromethane;
DOI:10.1016/0008-6215(83)88173-7