4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

Base Information

Chemical Name:4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine
CAS No.:1256783-97-7
Molecular Formula:C₂₅H₂₃FN₄OS
Molecular Weight:446.548
Hs Code.:

Synonyms:4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

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Chemical Property of 4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

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Technology Process of 4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

There total 1 articles about 4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57268-16-3
5-bromo-2-methyl-1,3-thiazole

: 1256784-60-7
4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

: 1256783-97-7
4-{5-[(4-fluorophenyl)methyl]-6-methylpyrimidin-4-yl}-7-(2-methyl-1,3-thiazol-5-yl)-2,3,4,5-tetrahydro-1,4-benzoxazepine

Guidance literature:: With potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; at 100 ℃; for 20h;