57268-16-3 Usage
Uses
Used in Pharmaceutical Industry:
5-Bromo-2-methylthiazole is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of novel therapeutic agents. Its unique chemical properties allow it to be incorporated into drug molecules, enhancing their efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Bromo-2-methylthiazole is utilized as a building block for the development of new agrochemicals, such as pesticides and herbicides. Its reactivity and structural features enable the creation of compounds with improved activity and selectivity against target pests and weeds.
Used in Organic Synthesis:
5-Bromo-2-methylthiazole serves as a reagent in organic synthesis, particularly for the creation of thiazole derivatives. Its high reactivity allows for the formation of a variety of thiazole-containing compounds, which are valuable in various applications, including as pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Fine Chemicals Industry:
5-Bromo-2-methylthiazole is employed as a building block in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, such as fragrances, dyes, and specialty materials. Its unique structure and reactivity contribute to the development of innovative and high-quality fine chemicals.
It is important to handle 5-Bromo-2-methylthiazole with proper precautions due to its strong odor and potential health risks when inhaled or ingested. Ensuring safe handling and storage practices is crucial to avoid any adverse effects on human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 57268-16-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,7,2,6 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 57268-16:
(7*5)+(6*7)+(5*2)+(4*6)+(3*8)+(2*1)+(1*6)=143
143 % 10 = 3
So 57268-16-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H4BrNS/c1-3-6-2-4(5)7-3/h2H,1H3
57268-16-3Relevant academic research and scientific papers
COURSE OF BROMINATION OF THIAZOLE AND 2-METHYLTHIAZOLE
Gol'dfarb, Ya. L.,Gromova, G. P.,Belen'kii, L. I.
, p. 663 - 666 (2007/10/02)
Bromination of thiazole by bromine in the presence of aluminium chloride in neutral solvent or without solvent takes place at the 2-position.Such an orientation contradicts the traditional addition-cleavage mechanism, and agrees with the ylid mechanism of electrophilic substitution. 2-Methylthiazole brominates at the 5-position, and the reaction is impeded in the presence of aluminium chloride; this is due to heterocycle deactivation by complexation with the Lewis acid at the nitrogen atom.
