2-phenyl-4-hydroxy-5-butylthiazole

Base Information

• Chemical Name: 2-phenyl-4-hydroxy-5-butylthiazole
• CAS No.: 131786-78-2
• Molecular Formula: C₁₃H₁₅NOS
• Molecular Weight: 233.334
• Mol file: 131786-78-2.mol

Synonyms:2-phenyl-4-hydroxy-5-butylthiazole

Chemical Property of 2-phenyl-4-hydroxy-5-butylthiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenyl-4-hydroxy-5-butylthiazole

There total 2 articles about 2-phenyl-4-hydroxy-5-butylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

methyl 2-bromohexanoate (5445-19-2) + benzenecarbothioamide (2227-79-4) → 2-phenyl-4-hydroxy-5-butylthiazole (131786-78-2)

Guidance literature:

With pyridine; In toluene; at 80 ℃; for 2h;

DOI:10.1021/jm00111a035

Reference yield:

→ 2-phenyl-4-hydroxy-5-butylthiazole (131786-78-2)

Guidance literature:

Reference yield: 81.0%

acetic anhydride (108-24-7) + 2-phenyl-4-hydroxy-5-butylthiazole (131786-78-2) → 2-phenyl-4-acetoxy-5-butylthiazole (131787-05-8)

Guidance literature:

With pyridine; In dichloromethane; at 23 ℃; for 10h;

DOI:10.1021/jm00111a035

upstream raw materials:

methyl 2-bromohexanoate

benzenecarbothioamide

Downstream raw materials:

2-phenyl-4-acetoxy-5-butylthiazole