C₂₇H₃₀F₂N₄O₄S

Base Information

• Chemical Name: C₂₇H₃₀F₂N₄O₄S
• CAS No.: 1616278-54-6
• Molecular Formula: C₂₇H₃₀F₂N₄O₄S
• Molecular Weight: 544.622
• Mol file: 1616278-54-6.mol

Synonyms:C₂₇H₃₀F₂N₄O₄S

Chemical Property of C₂₇H₃₀F₂N₄O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₀F₂N₄O₄S

There total 11 articles about C₂₇H₃₀F₂N₄O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 5-(5-(2,4-difluorobenzyl)-1,3,4-thiadiazol-2-yl)-3-methoxy-4-oxo-4H-pyran-2-carboxylate (1616277-96-3) + 1-(aminomethyl)-4-ethoxy-N-ethylcyclohexanamine (1616278-59-1) → C27H30F2N4O4S (1616278-55-7) + C27H30F2N4O4S (1616278-54-6)

Guidance literature:

With 1-methyl-1H-imidazole; at 65 ℃;

Reference yield:

tert-butyl 4-methoxy-3-oxobutanoate (74530-59-9) → C27H30F2N4O4S (1616278-55-7) + C27H30F2N4O4S (1616278-54-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: toluene / 2 h / 80 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere

2.2: 1 h / -70 °C

3.1: hydrogenchloride / ethyl acetate / 1 h / 0 - 20 °C

4.1: oxalyl dichloride; N,N-dimethyl-formamide / N,N-dimethyl-formamide; toluene / 2 h / 0 - 20 °C / Inert atmosphere

5.1: chloroform / 16 h / 20 °C

6.1: 1-methyl-1H-imidazole / 65 °C

With 1-methyl-1H-imidazole; hydrogenchloride; oxalyl dichloride; N,N-dimethyl-formamide; lithium hexamethyldisilazane; In tetrahydrofuran; chloroform; ethyl acetate; N,N-dimethyl-formamide; toluene;

Reference yield:

C12H21NO4 (1616277-93-0) → C27H30F2N4O4S (1616278-55-7) + C27H30F2N4O4S (1616278-54-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -70 °C / Inert atmosphere

1.2: 1 h / -70 °C

2.1: hydrogenchloride / ethyl acetate / 1 h / 0 - 20 °C

3.1: oxalyl dichloride; N,N-dimethyl-formamide / N,N-dimethyl-formamide; toluene / 2 h / 0 - 20 °C / Inert atmosphere

4.1: chloroform / 16 h / 20 °C

5.1: 1-methyl-1H-imidazole / 65 °C

With 1-methyl-1H-imidazole; hydrogenchloride; oxalyl dichloride; N,N-dimethyl-formamide; lithium hexamethyldisilazane; In tetrahydrofuran; chloroform; ethyl acetate; N,N-dimethyl-formamide; toluene;

upstream raw materials:

tert-butyl 4-methoxy-3-oxobutanoate

C₁₂H₂₁NO₄

C₁₄H₁₈O₇

C₁₀H₁₀O₇