methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Base Information

• Chemical Name: methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate
• CAS No.: 441769-11-5
• Molecular Formula: C₁₃H₂₂FNO₃
• Molecular Weight: 259.321

Synonyms:methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Chemical Property of methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

There total 3 articles about methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl trans-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (1138432-16-2) → methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (441769-11-5)

Guidance literature:

With palladium(II) hydroxide/carbon; hydrogen; In methanol; at 20 ℃; under 760.051 Torr;

DOI:10.1016/j.bmc.2008.12.026

Reference yield: 84.0%

methyl 4-[1-(tert-butoxycarbonyl)-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (1138432-15-1) → methyl 4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (441769-11-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1016/j.bmc.2008.12.026

Reference yield:

methyl cis-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (1138432-16-2) → methyl cis-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate (441769-11-5)

Guidance literature:

With palladium(II) hydroxide/carbon; hydrogen; In methanol; at 20 ℃; under 760.051 Torr;

DOI:10.1016/j.bmc.2008.12.026

upstream raw materials:

methyl 4-[1-(tert-butoxycarbonyl)-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

methyl cis-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

methyl trans-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Downstream raw materials:

C₂₉H₃₄FN₃O₅

methyl cis-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

methyl trans-4-[1-benzyloxycarbonyl-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

methyl 4-[1-(tert-butoxycarbonyl)-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 441769-11-5 methyl trans-4-[(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send