Technology Process of C27H25NO4
There total 8 articles about C27H25NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C20H19NO4; benzyl bromide;
In
tetrahydrofuran;
at -15 - 10 ℃;
for 0.333333h;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at -15 - 20 ℃;
for 18.5h;
With
sodium hydrogencarbonate;
In
tetrahydrofuran; water; mineral oil;
at -5 - 0 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 18.5 h / -15 - 20 °C / Inert atmosphere
2: pyridine / isopropyl alcohol / 8 h / 80 - 82 °C
3: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 18.5 h / -15 - 20 °C / Inert atmosphere
With
pyridine; sodium hydride;
tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; isopropyl alcohol; mineral oil;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Cumene hydroperoxide / titanium(IV) isopropylate; D-(-)-diisopropyl tartrate / dichloromethane / 18.08 h / -45 - -30 °C / Molecular sieve; Inert atmosphere
2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1.5 h / 0 - 23 °C / Inert atmosphere
3: potassium carbonate; water / methanol / 3 h / 10 - 23 °C
4: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 18.5 h / -15 - 20 °C / Inert atmosphere
5: pyridine / isopropyl alcohol / 8 h / 80 - 82 °C
6: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 18.5 h / -15 - 20 °C / Inert atmosphere
With
pyridine; Cumene hydroperoxide; di-isopropyl azodicarboxylate; water; sodium hydride; potassium carbonate; triphenylphosphine;
titanium(IV) isopropylate; tetra-(n-butyl)ammonium iodide; D-(-)-diisopropyl tartrate;
In
tetrahydrofuran; methanol; dichloromethane; isopropyl alcohol; mineral oil;