3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene

Base Information

• Chemical Name: 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene
• CAS No.: 1065524-61-9
• Molecular Formula: C₂₂H₂₉NO₇
• Molecular Weight: 419.475
• Mol file: 1065524-61-9.mol

Synonyms:3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene

Chemical Property of 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene

There total 1 articles about 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

3-(2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)propene (1065524-59-5) + (R,S)-2-chloropropionic acid (598-78-7) + methyl iodide (74-88-4) → 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene (1065524-61-9) + 3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((S)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene

Guidance literature:

3-(2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)propene; (R,S)-2-chloropropionic acid; With sodium hydride; In 1,4-dioxane; at 50 ℃; for 4h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Further stages.;

DOI:10.1016/j.tet.2008.07.009

Reference yield: 93.0%

3-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)propene (1065524-61-9) → 2-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)acetic acid (1065524-63-1)

Guidance literature:

With sodium periodate; ruthenium trichloride; In 1,4-dioxane; water; at 20 ℃;

DOI:10.1016/j.tet.2008.07.009

upstream raw materials:

3-(2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)propene

(R,S)-2-chloropropionic acid

methyl iodide

Downstream raw materials:

2-(2-acetamido-4,6-O-benzylidene-2-deoxy-3-((R)-1-(methoxycarbonyl)ethoxy)-α-D-glucopyranosyl)acetic acid