Sodium 3-phosphoglycerate

Base Information

• Chemical Name: Sodium 3-phosphoglycerate
• CAS No.: 17603-42-8
• Molecular Formula: C₃H₇O₆P*2Na
• Molecular Weight: 216.038
• Hs Code.: 2919900090
• Mol file: 17603-42-8.mol

Synonyms:1,2,3-Propanetriol,1-(dihydrogen phosphate), sodium salt (9CI);Glycerol, 1-(dihydrogen phosphate),sodium salt (8CI);Sodium 3-phosphoglycerate;Sodium DL-glycerophosphate;Sodium glycerophosphate;Sodium a-glycerophosphate;

Chemical Property of Sodium 3-phosphoglycerate

Chemical Property:

• Boiling Point: 119-121°C(lit.)
• Flash Point: 15°C
• PSA: 119.86000
• Density: 1.096g/mLat 25°C(lit.)
• LogP: -1.11290
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Sodium3-Phosphoglycerate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,F
• Hazard Codes: Xn,F

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium 3-phosphoglycerate can be used as a nutritional medicine. It is an intravenous phosphorus supplement to meet the body's daily phosphorus needs.

Technology Process of Sodium 3-phosphoglycerate

There total 4 articles about Sodium 3-phosphoglycerate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → Sodium beta-glycerophosphate (819-83-0) + disodium DL-α-glycerophosphate (1555-56-2,3325-00-6,6810-16-8,17603-42-8,35898-83-0,95648-81-0,110972-48-0,149675-96-7)

Guidance literature:

glycerol; With sodium dihydrogenphosphate; at 120 - 125 ℃; for 120h;

With sodium hydroxide; at 100 - 105 ℃; for 20h; Temperature;

Reference yield:

→ disodium DL-α-glycerophosphate (1555-56-2,3325-00-6,6810-16-8,17603-42-8,35898-83-0,95648-81-0,110972-48-0,149675-96-7)

Guidance literature:

With water;

Reference yield:

→ disodium DL-α-glycerophosphate (1555-56-2,3325-00-6,6810-16-8,17603-42-8,35898-83-0,95648-81-0,110972-48-0,149675-96-7)

Guidance literature:

With water;

upstream raw materials:

glycerol

epichlorohydrin

Downstream raw materials:

2-aminoethyl 2,3-dihydroxypropyl hydrogen phosphate

Refernces

Synthesis and biological activity of the trimethylsilyl ether of vitamin D₂

10.1007/BF00764628

The study focuses on the synthesis and biological activity of the trimethylsilyl ether of Vitamin D2, a compound of interest due to its potential to increase the stability of antirachitic preparations. The researchers synthesized Vitamin D2 trimethylsilyl ether (I) using a reaction involving hexamethyldisilazane and trimethylsilyl chloride, and then assessed its biological activity through various tests including calcium and phosphorus levels in blood, alkaline phosphatase activity, and the presence of a specific calcium-binding protein in the duodenal mucosa of Leghorn chicks. The results showed that the biological activity of the etherified Vitamin D2 was comparable to the non-etherified form, with some differences attributed to molecular mass and equimolar amounts. The study also examined the stability of the preparation over a six-month storage period, finding that the etherified form demonstrated greater stability, which was hypothesized to be due to the protective effects of the trimethylsilyl group against oxidation and degradation. The findings suggest that the use of silylated derivatives could reduce the loss of Vitamin D2 during storage, thereby increasing its economic value.