(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Base Information

Chemical Name:(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester
CAS No.:1071522-04-7
Molecular Formula:C₁₇H₂₂FNO₂
Molecular Weight:291.366
Hs Code.:

Synonyms:(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Suppliers and Price of (2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

There total 6 articles about (2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1071522-01-4,1630906-99-8
(2R,3S)-3-Amino-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester hydrochloride

: 459-57-4
4-fluorobenzaldehyde

: 1071522-04-7
(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Guidance literature:: With sodium acetate; sodium cyanoborohydride; silica gel; In methanol; sodium hydrogencarbonate; ethyl acetate;

Reference yield:

: 26843-47-0
bicyclo[2.2.2]octane-2-endo,3-endo-dicarboxylic acid anhydride

: 1071522-04-7
(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Quinine / ethyl acetate; toluene; tetrachloromethane; methanol

2: triethylamine; sodium azide; benzyl alcohol / dichloromethane; ethyl acetate; benzene; water; tetrahydrofuran

3: hydrogenchloride / palladium / ethyl acetate; 1,4-dioxane; diethyl ether

4: sodium acetate; sodium cyanoborohydride / silica gel / ethyl acetate; sodium hydrogencarbonate; methanol

With hydrogenchloride; sodium azide; sodium acetate; sodium cyanoborohydride; triethylamine; benzyl alcohol; Quinine; silica gel; palladium; In tetrahydrofuran; 1,4-dioxane; methanol; tetrachloromethane; diethyl ether; dichloromethane; water; sodium hydrogencarbonate; ethyl acetate; toluene; benzene;

Reference yield:

: 6708-37-8,85081-13-6,85081-14-7
bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic anhydride

: 1071522-04-7
(2R,3S)-3-(4-fluorobenzylamino)aminobicyclo[2.2.2]octane-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: palladium / ethyl acetate

2: Quinine / ethyl acetate; toluene; tetrachloromethane; methanol

3: triethylamine; sodium azide; benzyl alcohol / dichloromethane; ethyl acetate; benzene; water; tetrahydrofuran

4: hydrogenchloride / palladium / ethyl acetate; 1,4-dioxane; diethyl ether

5: sodium acetate; sodium cyanoborohydride / silica gel / ethyl acetate; sodium hydrogencarbonate; methanol

With hydrogenchloride; sodium azide; sodium acetate; sodium cyanoborohydride; triethylamine; benzyl alcohol; Quinine; silica gel; palladium; In tetrahydrofuran; 1,4-dioxane; methanol; tetrachloromethane; diethyl ether; dichloromethane; water; sodium hydrogencarbonate; ethyl acetate; toluene; benzene;