2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

Base Information

Chemical Name:2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol
CAS No.:115250-39-0
Molecular Formula:C38H45NO7
Molecular Weight:627.778
Hs Code.:2922199090
DSSTox Substance ID:DTXSID70704886
Mol file:115250-39-0.mol

Synonyms:Tetrabenzyl-voglibose(TBV);DTXSID70704886;AKOS025402027;AC-3386;2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

Suppliers and Price of 2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tetrabenzyl Voglibose
100mg
$ 446.00

TRC
TetrabenzylVoglibose
1g
$ 1355.00

TRC
TetrabenzylVoglibose
100mg
$ 175.00

Medical Isotopes, Inc.
TetrabenzylVoglibose
100 mg
$ 640.00

Crysdot
2-(((1S,2S,3R,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexyl)amino)propane-1,3-diol 95+%
1g
$ 785.00

Chemenu
Tetrabenzyl-voglibose 95%
1g
$ 636.00

American Custom Chemicals Corporation
TETRABENZYL-VOGLIBOSE 95.00%
5MG
$ 495.25

Alichem
2-(((1S,2S,3R,4S,5S)-2,3,4-Tris(benzyloxy)-5-((benzyloxy)methyl)-5-hydroxycyclohexyl)amino)propane-1,3-diol
1g
$ 714.00

Total 93 raw suppliers

Chemical Property of 2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

Chemical Property:

Vapor Pressure:6.73E-26mmHg at 25°C
Refractive Index:1.629
Boiling Point:784.1 °C at 760 mmHg
PKA:12.98±0.70(Predicted)
Flash Point:428 °C
PSA：109.64000
Density:1.24 g/cm³
LogP:4.79650
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:3.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:17
Exact Mass:627.31960277
Heavy Atom Count:46
Complexity:805

Purity/Quality:

99% ^*data from raw suppliers

Tetrabenzyl Voglibose ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(C(C1(COCC2=CC=CC=C2)O)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)NC(CO)CO
Isomeric SMILES:C1C([C@@H](C([C@@H]([C@]1(COCC2=CC=CC=C2)O)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)NC(CO)CO
Uses Tetrabenzyl-voglibose is a derivative of Voglibose which is an α-Glucosidase inhibitor used as an antidiabetic.

Technology Process of 2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol

There total 12 articles about 2-({(2S,4S,5S)-2,3,4-Tris(benzyloxy)-5-[(benzyloxy)methyl]-5-hydroxycyclohexyl}amino)propane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 115250-38-9
(1S)-(1(OH),2,4/1,3)-2,3,4-Tri-O-benzyl-1-C-<(benzyloxy)methyl>-5-oxo-1,2,3,4-cyclohexanetetrol

: 534-03-2
serinol

: 115250-39-0
(1S)-(1(OH),2,4,5/1,3)-2,3,4-tri-O-benzyl-5-<<2-hydroxy-1-(hydroxymethyl)ethyl>amino>-1-C-<(benzyloxy)methyl>-1,2,3,4-cyclohexanetetrol

Guidance literature:: With sodium cyanoborohydride; In methanol; for 16h; Ambient temperature;
DOI:10.1021/jo00039a026

Reference yield:

: 140926-94-9
tetra-O-benzylvaliolamine

: 534-03-2
serinol

: 115250-39-0
(1S)-(1(OH),2,4,5/1,3)-2,3,4-tri-O-benzyl-5-<<2-hydroxy-1-(hydroxymethyl)ethyl>amino>-1-C-<(benzyloxy)methyl>-1,2,3,4-cyclohexanetetrol

Guidance literature:: tetra-O-benzylvaliolamine; serinol; In methanol; at 20 ℃; for 1h;

With sodium cyanoborohydride; In methanol;

With hydrogenchloride; In methanol; water; pH=8.0;

Reference yield:

: 96-26-4,26776-70-5
dihydroxyacetone

: 140926-94-9
tetra-O-benzylvaliolamine

: 115250-39-0
(1S)-(1(OH),2,4,5/1,3)-2,3,4-tri-O-benzyl-5-<<2-hydroxy-1-(hydroxymethyl)ethyl>amino>-1-C-<(benzyloxy)methyl>-1,2,3,4-cyclohexanetetrol

Guidance literature:: dihydroxyacetone; tetra-O-benzylvaliolamine; In methanol; at 20 - 30 ℃; for 0.5 - 1h;

With hydrogenchloride; sodium cyanoborohydride; In methanol; water; pH=~ 6.0; Product distribution / selectivity;