1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Base Information

Chemical Name:1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol
CAS No.:167394-68-5
Molecular Formula:C₃₀H₃₄O₈
Molecular Weight:522.595
Hs Code.:

Synonyms:1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Suppliers and Price of 1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

There total 15 articles about 1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 161364-90-5
(2R,3R,4S,5R,6S)-2-acetoxy-3-hydroxy-4,5-bis-O-benzyl-6-O-[(4-methoxyphenyl)methyl]-cyclohexanone

: 167394-68-5
1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In acetonitrile; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.tetlet.2016.06.038

Reference yield:

: 90633-95-7,94827-31-3,90633-90-2
methyl 2,3-bis-O-benzyl-4-O-[(4-methoxyphenyl)methyl]-α-D-glucopyranoside

: 167394-68-5
1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) (COCl)2, DMSO; 2.) Et₃N / CH₂Cl₂ / 0.5 h / -78 °C

2: K₂CO₃ / acetonitrile / 20 h / Ambient temperature

3: 75 percent / mercuric acetate, aq. NaCl / acetone / 20 h / Ambient temperature

4: 63 percent / sodium triacetoxy borohydride / acetic acid; acetonitrile / 1 h / Ambient temperature

With oxalyl dichloride; mercury(II) diacetate; sodium tris(acetoxy)borohydride; potassium carbonate; dimethyl sulfoxide; triethylamine; sodium chloride; In dichloromethane; acetic acid; acetone; acetonitrile;
DOI:10.1016/S0040-4039(98)00737-0

Reference yield:

: 97-30-3
methyl-alpha-D-glucopyranoside

: 167394-68-5
1-O-acetyl-3,4-bis-O-benzyl-5-O-[(4-methoxyphenyl)methyl]-D-myo-inositol

Guidance literature:: Multi-step reaction with 7 steps

1: p-toluenesulfonic acid / dimethylformamide / 6 h / 65 °C

2: NaH / dimethylformamide / 5 h / Ambient temperature

3: 95 percent / lithium aluminum hydride, aluminum chloride / diethyl ether; CH₂Cl₂ / 3 h / 0 °C

4: 1.) (COCl)2, DMSO; 2.) Et₃N / CH₂Cl₂ / 0.5 h / -78 °C

5: K₂CO₃ / acetonitrile / 20 h / Ambient temperature

6: 75 percent / mercuric acetate, aq. NaCl / acetone / 20 h / Ambient temperature

7: 63 percent / sodium triacetoxy borohydride / acetic acid; acetonitrile / 1 h / Ambient temperature

With lithium aluminium tetrahydride; aluminium trichloride; oxalyl dichloride; mercury(II) diacetate; sodium tris(acetoxy)borohydride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; sodium chloride; In diethyl ether; dichloromethane; acetic acid; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1016/S0040-4039(98)00737-0