2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester

Base Information

• Chemical Name: 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester
• CAS No.: 868610-57-5
• Molecular Formula: C₂₄H₃₂N₂O₃
• Molecular Weight: 396.53
• Mol file: 868610-57-5.mol

Synonyms:2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester

Chemical Property of 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester

Chemical Property:

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Technology Process of 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester

There total 2 articles about 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

adamantan-2-amine hydrochloride (10523-68-9) + N-benzyloxycarbonyl D/L-pipecolinic acid (28697-07-6) → 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester (868610-57-5)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h;

Reference yield: 84.0%

→ 2-(adamantan-2-ylcarbarmoyl)-piperidine-1-carboxylic acid benzyl ester (868610-57-5)

Guidance literature:

upstream raw materials:

adamantan-2-amine hydrochloride

N-benzyloxycarbonyl D/L-pipecolinic acid