1,2,4-Tribromobutane

Base Information

• Chemical Name: 1,2,4-Tribromobutane
• CAS No.: 38300-67-3
• Molecular Formula: C4H7Br3
• Molecular Weight: 294.812
• Hs Code.: 2903399090
• Mol file: 38300-67-3.mol

Synonyms:1,2,4-TRIBROMOBUTANE;Butane, 1,2,4-tribromo-;butane,1,2,4-tribromo-;1.2.4-TRIBROMOBUTANE,=99%

Chemical Property of 1,2,4-Tribromobutane

Chemical Property:

• Vapor Pressure: 0.0336mmHg at 25°C
• Melting Point: -18°C
• Refractive Index: 1.563
• Boiling Point: 250.8 °C at 760 mmHg
• Flash Point: 104.9 °C
• PSA: 0.00000
• Density: 2.192 g/cm³
• LogP: 2.92980

Purity/Quality:

99% ^*data from raw suppliers

1,2,4-TRIBROMOBUTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2,4-Tribromobutane

There total 16 articles about 1,2,4-Tribromobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-bromo-4-butene (5162-44-7) → 1,3,4-Tribromobutane (38300-67-3)

Guidance literature:

With bromine; In dichloromethane; at -5 - 5 ℃;

DOI:10.1021/op3001788

Reference yield: 5.0%

Cyclopropylmethanol (2516-33-8) → 1,3,4-Tribromobutane (38300-67-3) + Cyclopropanecarboxaldehyde (1489-69-6)

Guidance literature:

Cyclopropylmethanol; With N,N-dimethylthiourea; In dichloromethane; at 20 ℃;

With N-Bromosuccinimide; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1021/acs.joc.0c01431

Reference yield: 4.0%

1-bromo-4-butene (5162-44-7) → 1,3,4-Tribromobutane (38300-67-3) + 1,4-Dibromo-2-fluorobutane (112464-88-7) + 2,4-Dibromo-1-fluorobutane

Guidance literature:

With N-Bromosuccinimide; trimethylamine trihydrofluoride; In dichloromethane; at 0 - 20 ℃; Title compound not separated from byproducts;

DOI:10.1016/S0022-1139(99)00230-4

upstream raw materials:

1-bromo-4-butene

1,4-dibromo-2-butene

3,4-Dibromobutan-1-ol

1,2-dibromo-4-methoxy-butane

Downstream raw materials:

3-Hydroxytetrahydrofuran

pent-4-enoic acid

2,4-dibromo-1-butene

1-phenyl-4-penten-1-ol

Refernces

• 1、 Karki, Megha,Magolan, Jakob. "Bromination of olefins with HBr and DMSO". . p. 3701 - 3707. Retrieved 2015/04/22.
• 2、 Lübke, Martin,Skupin, Rolf,Haufe, Günter. "Regioselectivity of bromofluorination of functionalized 1-alkenes". . p. 125 - 133. Retrieved 2007/10/03.