4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

Base Information

Chemical Name:4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide
CAS No.:1215634-37-9
Molecular Formula:BrH*C₈H₈BrNO₃
Molecular Weight:326.972
Hs Code.:

Synonyms:4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

Suppliers and Price of 4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of 4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

There total 1 articles about 4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3177-80-8
2-amino-3-methoxybenzoic acid

: 1215634-37-9
4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

Guidance literature:: With bromine; In chloroform; at 0 - 20 ℃; for 16h;

Reference yield:

: 1215634-37-9
4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

: 1616829-84-5
8-hydroxy-6-(5-methyl-3-phenylisoxazol-4-yl)quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 6 steps

1: 12 h / 150 °C

2: hydrogen bromide; water / acetic acid / 96 h / 130 °C

3: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.5 h / 80 °C / Cooling with ice

4: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 5 h / 100 °C

5: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / N,N-dimethyl-formamide; water / 80 - 100 °C / Sealed tube

6: formic acid / water / 80 - 100 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; formic acid; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; water; hydrogen bromide; potassium acetate; sodium hydride; potassium carbonate; In 1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 1215634-37-9
4-bromo-2-carboxy-6-methoxybenzenamine hydrobromide

: 1616830-32-0
6-(2-benzylphenyl)-8-((2-(trimethylsilyl)ethoxy)methoxy)-3-((2-(trimethylsilyl)ethoxy)methyl)quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 5 steps

1: 12 h / 150 °C

2: hydrogen bromide; water / acetic acid / 96 h / 130 °C

3: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.5 h / 80 °C / Cooling with ice

4: potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 5 h / 100 °C

5: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane; water / 6 h / 90 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; water; hydrogen bromide; potassium acetate; sodium hydride; potassium carbonate; In 1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide; mineral oil;