C₃₀H₂₆N₄O₂

Base Information

• Chemical Name: C₃₀H₂₆N₄O₂
• CAS No.: 1352035-42-7
• Molecular Formula: C₃₀H₂₆N₄O₂
• Molecular Weight: 474.562
• Mol file: 1352035-42-7.mol

Synonyms:C₃₀H₂₆N₄O₂

Chemical Property of C₃₀H₂₆N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₆N₄O₂

There total 7 articles about C₃₀H₂₆N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

3-([1,1:3',1''-terphenyl]-5'-yl)-1-chloro-6,7-dimethoxyisoquinoline (1352036-18-0) + guanidine hydrochloride (50-01-1) → C30H26N4O2 (1352035-42-7)

Guidance literature:

guanidine hydrochloride; With sodium hydride; In dimethyl sulfoxide; mineral oil; at 60 ℃; for 0.5h;

3-([1,1:3',1''-terphenyl]-5'-yl)-1-chloro-6,7-dimethoxyisoquinoline; chloro(2-di-t-butylphosphino-2',4',6'-tri-1-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]pd(II); In dimethyl sulfoxide; mineral oil; at 100 ℃;

Reference yield:

5,6-dimethoxy-1-indanone (2107-69-9) → C30H26N4O2 (1352035-42-7)

Guidance literature:

Multi-step reaction with 7 steps

1.1: hydrogenchloride; n-Butyl nitrite / water; methanol / 2.5 h / 40 °C

2.1: sodium hydroxide; p-toluenesulfonyl chloride / water / 0.25 h / 50 - 80 °C

2.2: pH 3 - 4

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

4.1: hydrogen bromide / diethyl ether / 2 h

5.1: potassium carbonate / palladium diacetate; XPhos / acetonitrile; water / 1.5 h / 100 °C

6.1: trichlorophosphate / 3 h / 110 °C

7.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0.5 h / 60 °C

7.2: 100 °C

With hydrogenchloride; oxalyl dichloride; n-Butyl nitrite; hydrogen bromide; sodium hydride; potassium carbonate; p-toluenesulfonyl chloride; sodium hydroxide; trichlorophosphate; palladium diacetate; N,N-dimethyl-formamide; XPhos; In methanol; diethyl ether; dichloromethane; water; dimethyl sulfoxide; acetonitrile; mineral oil;

Reference yield:

2-(cyanomethyl)-4,5-dimethoxybenzoic acid (76254-26-7) → C30H26N4O2 (1352035-42-7)

Guidance literature:

Multi-step reaction with 5 steps

1.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

2.1: hydrogen bromide / diethyl ether / 2 h

3.1: potassium carbonate / palladium diacetate; XPhos / acetonitrile; water / 1.5 h / 100 °C

4.1: trichlorophosphate / 3 h / 110 °C

5.1: sodium hydride / dimethyl sulfoxide; mineral oil / 0.5 h / 60 °C

5.2: 100 °C

With oxalyl dichloride; hydrogen bromide; sodium hydride; potassium carbonate; trichlorophosphate; palladium diacetate; N,N-dimethyl-formamide; XPhos; In diethyl ether; dichloromethane; water; dimethyl sulfoxide; acetonitrile; mineral oil;

upstream raw materials:

3-([1,1:3',1''-terphenyl]-5'-yl)-1-chloro-6,7-dimethoxyisoquinoline

guanidine hydrochloride

5,6-dimethoxy-1-indanone

2-(cyanomethyl)-4,5-dimethoxybenzoic acid

Refernces