4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

Base Information

Chemical Name:4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol
CAS No.:1446017-75-9
Molecular Formula:C₂₅H₂₄N₂O₃S
Molecular Weight:432.543
Hs Code.:

Synonyms:4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

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Chemical Property of 4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

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Technology Process of 4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

There total 7 articles about 4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₂₂N₂O₃S

: 1446017-75-9
4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃;
DOI:10.1016/j.ejmech.2014.07.072

Reference yield:

: 22966-19-4
trans-4'-methoxychalcone

: 1446017-75-9
4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

Guidance literature:: Multi-step reaction with 5 steps

1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

2: aluminum (III) chloride; bromine / chloroform / 6 h / 20 °C

3: sodium acetate / ethanol / 80 °C

4: toluene-4-sulfonic acid / toluene / 130 °C

5: sodium tetrahydroborate / ethanol / 20 °C

With aluminum (III) chloride; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; bromine; sodium acetate; toluene-4-sulfonic acid; In ethanol; chloroform; ethyl acetate; toluene;
DOI:10.1016/j.ejmech.2014.07.072

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 1446017-75-9
4-((5-benzyl-4-(4-methoxyphenyl)thiazol-2-ylamino)methyl)-2-methoxyphenol

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydroxide / ethanol; water / 0.17 h / 20 °C

1.2: 20 °C

2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3.1: aluminum (III) chloride; bromine / chloroform / 6 h / 20 °C

4.1: sodium acetate / ethanol / 80 °C

5.1: toluene-4-sulfonic acid / toluene / 130 °C

6.1: sodium tetrahydroborate / ethanol / 20 °C

With aluminum (III) chloride; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; bromine; sodium acetate; toluene-4-sulfonic acid; sodium hydroxide; In ethanol; chloroform; water; ethyl acetate; toluene;
DOI:10.1016/j.ejmech.2014.07.072