2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane

Base Information

• Chemical Name: 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane
• CAS No.: 76685-89-7
• Molecular Formula: C₂₂H₃₀O₃
• Molecular Weight: 342.478
• Mol file: 76685-89-7.mol

Synonyms:2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane

Chemical Property of 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane

There total 8 articles about 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

C24H37NO4 → 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane (76685-89-7)

Guidance literature:

at 135 ℃; under 0.1 Torr;

DOI:10.1016/S0040-4039(00)93155-1

Reference yield:

1-(2-chloroethyl)-3-methoxybenzene (73004-96-3) → 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane (76685-89-7)

Guidance literature:

Multi-step reaction with 5 steps

1: Mg

2: 83 percent / xylene / Heating

3: 88 percent / LiAlH₄ / diethyl ether

4: 85 percent / m-Chloroperbenzoic acid

5: 60 percent / 135 °C / 0.1 Torr

With lithium aluminium tetrahydride; magnesium; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; xylene;

DOI:10.1016/S0040-4039(00)93155-1

Reference yield:

[2-Methyl-3-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-1-enyl]-methanol → 2-{3-[3-(3-Methoxy-phenyl)-prop-(E)-ylidene]-2-methyl-2-vinyl-cyclopentyl}-2-methyl-[1,3]dioxolane (76685-89-7)

Guidance literature:

Multi-step reaction with 6 steps

1: 62 percent / Pyridinium chlorochromate

2: Mg

3: 83 percent / xylene / Heating

4: 88 percent / LiAlH₄ / diethyl ether

5: 85 percent / m-Chloroperbenzoic acid

6: 60 percent / 135 °C / 0.1 Torr

With lithium aluminium tetrahydride; magnesium; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; In diethyl ether; xylene;

DOI:10.1016/S0040-4039(00)93155-1

upstream raw materials:

1-(2-chloroethyl)-3-methoxybenzene

2-Methyl-3-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-1-enecarbaldehyde

2-Methyl-3-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-1-enecarboxylic acid ethyl ester

3-(3-Methoxy-phenyl)-1-[2-methyl-3-(2-methyl-[1,3]dioxolan-2-yl)-cyclopent-1-enyl]-propan-1-ol

Downstream raw materials:

(3aR,4R,7aR)-4-[2-(3-Methoxy-phenyl)-ethyl]-7a-methyl-1-(2-methyl-[1,3]dioxolan-2-yl)-octahydro-inden-5-one