8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Base Information

Chemical Name:8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril
CAS No.:74245-70-8
Molecular Formula:C₃₂H₃₈N₂O₇
Molecular Weight:562.663
Hs Code.:

Synonyms:8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Suppliers and Price of 8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

There total 13 articles about 8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.4%

: 74245-69-5
5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-8-hydroxy-3,4-dihydrocarbostyril hydrochloride

: 78-95-5
chloroacetone

: 74245-70-8
8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Guidance literature:: With potassium carbonate; In water; acetone; for 4h; Heating;
DOI:10.1248/cpb.29.2166

Reference yield:

: 51973-93-4
N-benzyl-2-(3,4-dimethoxyphenyl)ethylamine

: 74245-70-8
(R)(+)-8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) conc. HCl / 1.) methanol, 4.5 h, reflux, 2.) acetone, 20 min, ice bath, overnight, room temperature

2: 1.) NaHCO₃, 2.) K₂CO₃ / acetone; H₂O / 2 h / Heating

With hydrogenchloride; sodium hydrogencarbonate; potassium carbonate; In water; acetone;
DOI:10.1248/cpb.29.2157

Reference yield:

: 51973-93-4
N-benzyl-2-(3,4-dimethoxyphenyl)ethylamine

: 74245-70-8
(S)(-)-8-acetonyloxy-5-<3-(N-benzyl-3,4-dimethoxyphenethylamino)-2-hydroxypropoxy>-3,4-dihydrocarbostyril

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) conc. HCl / 1.) methanol, 4.5 h, reflux, 2.) acetone, 20 min, ice bath, overnight, room temperature

2: 1.) NaHCO₃, 2.) K₂CO₃ / acetone; H₂O / 2 h / Heating

With hydrogenchloride; sodium hydrogencarbonate; potassium carbonate; In water; acetone;
DOI:10.1248/cpb.29.2157