Boc-MeβAla-OCH2cHex

Base Information

• Chemical Name: Boc-MeβAla-OCH2cHex
• CAS No.: 654651-68-0
• Molecular Formula: C₁₆H₂₉NO₄
• Molecular Weight: 299.411
• Mol file: 654651-68-0.mol

Synonyms:Boc-MeβAla-OCH2cHex

Chemical Property of Boc-MeβAla-OCH2cHex

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-MeβAla-OCH2cHex

There total 1 articles about Boc-MeβAla-OCH2cHex which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-t-butoxycarbonyl-N-methyl-β-alanine (124072-61-3) + cyclohexylmethyl alcohol (100-49-2) + benzyl alcohol (100-51-6,185532-71-2) → Boc-MeβAla-OCH2cHex (654651-68-0)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1248/cpb.51.759

Reference yield:

Boc-MeβAla-OCH2cHex (654651-68-0) → HCl*H-MeβAla-OCH2cHex

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃;

DOI:10.1248/cpb.51.759

Reference yield:

Boc-MeβAla-OCH2cHex (654651-68-0) → H-Tyr-D-MetO-Phe-MeβAla-OCH2cHex

Guidance literature:

Multi-step reaction with 3 steps

1: aq. HCl / ethyl acetate / 20 °C

2: 70 percent / EDC*HCl; HOBt; TEA / dimethylformamide / -10 - 20 °C

3: TFA / 1 h / 20 °C

With hydrogenchloride; TEA; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1248/cpb.51.759

upstream raw materials:

N-t-butoxycarbonyl-N-methyl-β-alanine

cyclohexylmethyl alcohol

benzyl alcohol

Downstream raw materials:

Boc-Tyr-D-MetO-Phe-MeβAla-OCH2cHex