Technology Process of 2-[(S)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-thiazole
There total 11 articles about 2-[(S)-2-Benzyloxy-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-thiazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
tri-n-butyl-tin hydride; di(1H-imidazol-2-yl)methanethione;
Multistep reaction;
1) THF, reflux; 2) toluene, reflux;
- Guidance literature:
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Multi-step reaction with 2 steps
1: 2) nBu4NF / 1) CH2Cl2, 10 h, room temp.; 2) THF, 2 h
2: 1) thiocarbonyl diimidazole; 2) nBu3SnH / 1) THF, reflux; 2) toluene, reflux
With
tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; di(1H-imidazol-2-yl)methanethione;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1) NaH; 2) nBu4NI / 1) THf, 30 min., room temp.; 2) 3 h
3: 2) nBu4NF / 1) CH2Cl2, 10 h, room temp.; 2) THF, 2 h
4: 1) thiocarbonyl diimidazole; 2) nBu3SnH / 1) THF, reflux; 2) toluene, reflux
With
tetrabutyl ammonium fluoride; tri-n-butyl-tin hydride; tetra-(n-butyl)ammonium iodide; sodium hydride; di(1H-imidazol-2-yl)methanethione;
