C₁₆H₁₇NO₃

Base Information

• Chemical Name: C₁₆H₁₇NO₃
• CAS No.: 85002-60-4
• Molecular Formula: C₁₆H₁₇NO₃
• Molecular Weight: 271.316
• Mol file: 85002-60-4.mol

Synonyms:C₁₆H₁₇NO₃

Chemical Property of C₁₆H₁₇NO₃

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₆H₁₇NO₃

There total 1 articles about C₁₆H₁₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

2-(4'-ethylphenyl)ethanol (22545-13-7) + 4-chlorobenzonitrile (100-00-5) → C16H17NO3 (85002-60-4)

Guidance literature:

With sodium hydride; In dimethyl sulfoxide; at 70 ℃; for 0.5h;

DOI:10.1248/cpb.30.3580

Reference yield:

C16H17NO3 (85002-60-4) → 4-[2-(4-Ethyl-phenyl)-ethoxy]-phenylamine

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;

DOI:10.1248/cpb.30.3580

Reference yield:

C16H17NO3 (85002-60-4) → 2-Chloro-3-{4-[2-(4-ethyl-phenyl)-ethoxy]-phenyl}-propionic acid methyl ester (85003-17-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen / 10percent Pd-C / methanol / 760 Torr / Ambient temperature

2: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) acetone, water, 5 deg C, 30 min, 2.) acetone, water, 35 deg C

With copper(I) oxide; hydrogenchloride; hydrogen; sodium nitrite; palladium on activated charcoal; In methanol;

DOI:10.1248/cpb.30.3580

upstream raw materials:

2-(4'-ethylphenyl)ethanol

4-chlorobenzonitrile

Downstream raw materials:

2-Chloro-3-{4-[2-(4-ethyl-phenyl)-ethoxy]-phenyl}-propionic acid methyl ester

5-{[4-[2-(5-ethylpyridin-2-ylo)ethoxy]phenyl]methyl}thiazolidine-2,4-dione