α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide

Base Information

• Chemical Name: α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide
• CAS No.: 1021879-82-2
• Molecular Formula: C₁₂H₁₇N₄O₄PS
• Molecular Weight: 344.331
• Mol file: 1021879-82-2.mol

Synonyms:α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide

Chemical Property of α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide

There total 3 articles about α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfide (1003924-50-2) → α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide (1021879-82-2)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2008.01.082

Reference yield:

diethyl (p-toluenesulfonyloxymethane)phosphonate (31618-90-3) → α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide (1021879-82-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In chloroform; N,N-dimethyl-formamide;

Reference yield:

1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfoxide (1021879-82-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

2: 3-chloro-benzenecarboperoxoic acid / chloroform / 20 °C

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In chloroform; N,N-dimethyl-formamide;

upstream raw materials:

α-(diethoxyphosphoryl)methyl 5-(1-phenyl)-1H-tetrazolyl sulfide

diethyl (p-toluenesulfonyloxymethane)phosphonate

1-Phenyl-1H-tetrazole-5-thiol

Downstream raw materials:

phenyl-1H-tetrazole

diethoxyphosphorylthioformic acid pyrrolidide

diethoxyphosphorylthioformic acid piperidide

3,4-dimethyl-6-(diethoxyphosphoryl)-2H-thiopyran