C₁₆H₁₆N₄O

Base Information

Chemical Name:C₁₆H₁₆N₄O
CAS No.:1427278-40-7
Molecular Formula:C₁₆H₁₆N₄O
Molecular Weight:280.329
Hs Code.:

C<sub>16</sub>H<sub>16</sub>N<sub>4</sub>O

Synonyms:C₁₆H₁₆N₄O

Suppliers and Price of C₁₆H₁₆N₄O

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₁₆N₄O

Chemical Property:

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Technology Process of C₁₆H₁₆N₄O

There total 3 articles about C₁₆H₁₆N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1414859-08-7
C₁₆H₁₆ClNO

: 1427278-40-7
C₁₆H₁₆N₄O

Guidance literature:: With trimethylsilylazide; tetrabutyl ammonium fluoride; In neat (no solvent); at 85 ℃; for 96h; Cooling with ice;
DOI:10.1021/ic3020749

Reference yield:

: 745075-80-3
2-chloro-6,7-dihydro-4-methyl-5H-cyclopenta[b]pyridin-7-ol

: 1427278-40-7
C₁₆H₁₆N₄O

Guidance literature:: Multi-step reaction with 4 steps

1.1: Novozyme 435 / 4 h / 20 °C

2.1: lithium hydroxide monohydrate

3.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C

3.2: 1 h / 0 °C

4.1: trimethylsilylazide; tetrabutyl ammonium fluoride / neat (no solvent) / 96 h / 85 °C / Cooling with ice

With lithium hydroxide monohydrate; trimethylsilylazide; tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran;
DOI:10.1021/ic3020749

Reference yield:

: 1263428-81-4
C₁₁H₁₂ClNO₂

: 1427278-40-7
C₁₆H₁₆N₄O

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium hydroxide monohydrate

2.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C

2.2: 1 h / 0 °C

3.1: trimethylsilylazide; tetrabutyl ammonium fluoride / neat (no solvent) / 96 h / 85 °C / Cooling with ice

With lithium hydroxide monohydrate; trimethylsilylazide; tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran;
DOI:10.1021/ic3020749