propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate

Base Information Edit

Chemical Name:propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
CAS No.:145773-22-4
Molecular Formula:C₂₆H₄₀O₅
Molecular Weight:432.601
Hs Code.:2937500000
European Community (EC) Number:687-773-3
UNII:P840K2J2DL
ChEMBL ID:CHEMBL84514
Mol file:145773-22-4.mol

Synonyms:15(S)-Latanoprost;145773-22-4;15-epi-Latanoprost;Latanoprost, (15S)-;P840K2J2DL;propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate;5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3S)-3-hydroxy-5-phenylpentyl)cyclopentyl)-, 1-methylethyl ester, (5Z)-;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]-, 1-methylethyl ester, (5Z)-;Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3S)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate;(15S)-Latanoprost;(Z)-isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate;15beta-Latanoprost;15-epi Latanoprost;starbld0018625;UNII-P840K2J2DL;15.BETA.-LATANOPROST;CHEMBL84514;SCHEMBL12775718;PD021272;LATANOPROST IMPURITY E [EP IMPURITY];5-HEPTENOIC ACID, 7-(3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYLPENTYL)CYCLOPENTYL)-, 1-METHYLETHYL ESTER, (1R-(1.ALPHA.(Z),2.BETA.(S*),3.ALPHA.,5.ALPHA.))-;5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)-, 1-methylethyl ester, (1R-(1alpha(Z),2beta(S*),3alpha,5alpha))-

Suppliers and Price of propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(15S)-Latanoprost
5mg
$ 250.00

Sigma-Aldrich
Latanoprost Related Compound B
25mg
$ 1550.00

Cayman Chemical
15(S)-Latanoprost ≥98%
10mg
$ 472.00

Cayman Chemical
15(S)-Latanoprost ≥98%
5mg
$ 266.00

Cayman Chemical
15(S)-Latanoprost ≥98%
1mg
$ 59.00

Cayman Chemical
15(S)-Latanoprost ≥98%
50mg
$ 1475.00

AvaChem
15(S)-Latanoprost
10mg
$ 890.00

AvaChem
15(S)-Latanoprost
5mg
$ 490.00

AvaChem
15(S)-Latanoprost
100mg
$ 2200.00

American Custom Chemicals Corporation
15(S)-LATANOPROST 95.00%
10MG
$ 11550.00

Total 36 raw suppliers

Chemical Property of propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.538
Boiling Point:583.839 °C at 760 mmHg
PKA:14.84±0.70(Predicted)
Flash Point:188.312 °C
PSA：86.99000
Density:1.094 g/cm³
LogP:4.18640
Storage Temp.:−20°C
XLogP3:4.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:14
Exact Mass:432.28757437
Heavy Atom Count:31
Complexity:526

Purity/Quality:

98%,99%, ^*data from raw suppliers

(15S)-Latanoprost ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xi
Hazard Codes:F,Xi
Statements: 11-36-66-67
Safety Statements: 16-26-29-33

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)OC(=O)CCCC=CCC1C(CC(C1CCC(CCC2=CC=CC=C2)O)O)O
Isomeric SMILES:CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1CC[C@@H](CCC2=CC=CC=C2)O)O)O
Uses An impurity of commercially prepared Latanoprost (L177280). An impurity of commercially prepared Latanoprost (L177280). Latanoprost USP Related Compound B.

Technology Process of propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate

There total 161 articles about propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3S)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.83%