9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Base Information

Chemical Name:9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester
CAS No.:628686-53-3
Molecular Formula:C₅₇H₇₆O₁₃Si
Molecular Weight:997.308
Hs Code.:

9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Synonyms:9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Suppliers and Price of 9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

There total 15 articles about 9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 108-24-7
acetic anhydride

: 282107-59-9
8-(methoxycarbonyl)octyl 2-O-(3-O-benzyl-5-O-tert-butyldiphenylsilyl)-β-D-arabinofuranosyl)-3-O-benzyl-5-O-pivaloyl-α-D-arabinofuranoside

: 628686-53-3
9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Guidance literature:: With pyridine; In ethyl acetate;
DOI:10.1002/ejoc.200300303

Reference yield:

: 282107-57-7
ethyl 3-O-benzyl-5-O-tert-butyldiphenylsilyl-2-O-(4-methoxybenzyl)-1-thio-α-D-arabinofuranoside

: 628686-53-3
9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: DDQ; 4A MS / CH₂Cl₂ / 2.5 h / 20 °C

1.2: 63 percent / IDCP; 4A MS / CH₂Cl₂ / 2 h / 20 °C

2.1: 99 percent / pyridine / ethyl acetate

With pyridine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; ethyl acetate;
DOI:10.1002/ejoc.200300303

Reference yield:

: 100-39-0
benzyl bromide

: 628686-53-3
9-[(2S,3S,4R,5R)-3-[(2S,3S,4R,5R)-3-Acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-2-yloxy]-4-benzyloxy-5-(2,2-dimethyl-propionyloxymethyl)-tetrahydro-furan-2-yloxy]-nonanoic acid methyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 90 percent / NaH / dimethylformamide / 1 h / 20 °C

2: SnCl₄; 4 Angstroem molecular sieves / CH₂Cl₂ / 3 h / 20 °C

3: 60 percent / MeONa / methanol / 1 h / 20 °C

4: 80 percent / DMAP; pyridine / 1.5 h / 0 °C

5: 84 percent / DDQ; 4 Angstroem molecular sieves / CH₂Cl₂ / 2.5 h / 0 - 20 °C

6: 73 percent / iodonium dicollidine perchlorate; 4 Angstroem molecular sieves / CH₂Cl₂ / 1.5 h / 20 °C

7: pyridine / CH₂Cl₂ / 20 °C

With pyridine; dmap; iodonium di(2,4,6-trimethylpyridine) perchlorate; 4 A molecular sieve; sodium methylate; tin(IV) chloride; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; N,N-dimethyl-formamide; 1: Etherification / 2: Ring cleavage / 3: Deacylation / 4: Acylation / 5: Condensation / 6: Intramolecular glycosylation / 7: Acetylation;
DOI:10.1039/b000873g