N-(4-METHOXYPHENYL)-2-NITROBENZENAMINE

Base Information

• Chemical Name: N-(4-METHOXYPHENYL)-2-NITROBENZENAMINE
• CAS No.: 54381-13-4
• Molecular Formula: C13H12N2O3
• Molecular Weight: 244.25
• Hs Code.: 2922199090
• Mol file: 54381-13-4.mol

Synonyms:(4-Methoxyphenyl)(2-nitrophenyl)amine;2-Nitro-N-(4-methoxyphenyl)benzenamine;4'-Methoxy-2-nitrodiphenylamine;N-(2-Nitrophenyl)-p-anisidine;

Chemical Property of N-(4-METHOXYPHENYL)-2-NITROBENZENAMINE

Chemical Property:

• Melting Point: 89 °C
• Boiling Point: 387.9 °C at 760 mmHg
• PKA: -2.70±0.40(Predicted)
• Flash Point: 188.4 °C
• PSA: 67.08000
• Density: 1.276 g/cm³
• LogP: 3.94320
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

N-(4-Methoxyphenyl)-2-nitroaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-METHOXYPHENYL)-2-NITROBENZENAMINE

There total 11 articles about N-(4-METHOXYPHENYL)-2-NITROBENZENAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methoxy-aniline (104-94-9) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → 2-nitro-4'-methoxydiphenylamine (54381-13-4)

Guidance literature:

at 110 ℃;

Reference yield: 95.0%

4-methoxy-aniline (104-94-9) + 2-Chloronitrobenzene (88-73-3) → 2-nitro-4'-methoxydiphenylamine (54381-13-4)

Guidance literature:

With potassium acetate; [(2,6-bis(2,4,6-triisopropylphenyl)phenyl)dicyclohexylphosphine](allyl-η³)palladium(II) chloride; In tert-butyl alcohol; at 100 ℃; for 12h; Solvent; Inert atmosphere; Sealed tube;

Reference yield: 85.0%

→ 2-nitro-4'-methoxydiphenylamine (54381-13-4)

Guidance literature:

With potassium fluoride; potassium carbonate; In N,N-dimethyl-formamide; at 130 ℃;

upstream raw materials:

4-methoxy-aniline

2-Chloronitrobenzene

ortho-nitrofluorobenzene

2-nitrophenyl bromide

Downstream raw materials:

N-(4-methoxyphenyl)benzimidazole

2-chloromethyl-1-(4-methoxy-phenyl)-1H-benzimidazole

1-(4-methoxyphenyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one

1-(4-methoxyphenyl)-2,3-dihydro-1H-1,3-benzodiazole-2-thione