α-allylbutyrophenone

Base Information

• Chemical Name: α-allylbutyrophenone
• CAS No.: 53546-37-5
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 188.269
• Mol file: 53546-37-5.mol

Synonyms:α-allylbutyrophenone

Chemical Property of α-allylbutyrophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-allylbutyrophenone

There total 5 articles about α-allylbutyrophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

diallylcarbonate (15022-08-9) + (Z)-trimethyl((1-phenylbut-1-en-1-yl)oxy)silane (120869-79-6) → α-allylbutyrophenone (53546-37-5)

Guidance literature:

With 1,2-bis-(diphenylphosphino)ethane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; for 12h; Heating;

DOI:10.1246/cl.1983.1325

Reference yield:

butyrophenone iminate (77821-53-5) + allyl bromide (106-95-6) → α-allylbutyrophenone (53546-37-5)

Guidance literature:

With hydrogenchloride; ethylmagnesium bromide; Multistep reaction; 1) THF, reflux, 1 h; 2) reflux, 18 h; 3) reflux, 3 h;

DOI:10.1021/ja00403a035

Reference yield:

propiophenone (495-40-9) → α-allylbutyrophenone (53546-37-5)

Guidance literature:

With sodium amide; Behandeln mit Allyljodid in siedendem Benzol;

DOI:10.1177/107110070002101015

upstream raw materials:

propiophenone

diallylcarbonate

(Z)-trimethyl((1-phenylbut-1-en-1-yl)oxy)silane

butyrophenone iminate

Downstream raw materials:

2-ethyl-2-methyl-1-phenyl-pent-4-en-1-one

2-ethyl-2-allyl-1-phenyl-pent-4-en-1-one

2-phenylbicyclo[2.2.1]heptan-2-ol

1-Phenylpent-4-en-1-one