(Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide

Base Information

• Chemical Name: (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide
• CAS No.: 1186132-32-0
• Molecular Formula: C₂₂H₂₃NO₃S
• Molecular Weight: 381.496
• Mol file: 1186132-32-0.mol

Synonyms:(Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide

Chemical Property of (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide

There total 3 articles about (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

C28H37NO3SSi (1186132-48-8) → (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide (1186132-32-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/adsc.200800628

Reference yield:

C24H25NO4S → (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide (1186132-32-0)

Guidance literature:

With methanol; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1055/s-0037-1610750

Reference yield:

4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide (125640-81-5) → (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide (1186132-32-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere

1.2: 6 h / Inert atmosphere

2.1: potassium carbonate; methanol / N,N-dimethyl-formamide / 4 h / 20 °C / Inert atmosphere

With methanol; sodium hydride; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1055/s-0037-1610750

upstream raw materials:

C₂₈H₃₇NO₃SSi

4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide

Downstream raw materials:

3-tosyl-1-vinyl-1,2,3,4-tetrahydrobenzo[f]isoquinoline