Technology Process of (R)-[(nonadec-1-en-4-yloxy)methyl]benzene
There total 3 articles about (R)-[(nonadec-1-en-4-yloxy)methyl]benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-nonadec-1-en-4-ol;
With
sodium hydride;
In
tetrahydrofuran;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
benzyl bromide;
at 0 - 20 ℃;
for 12h;
In
tetrahydrofuran;
Inert atmosphere;
DOI:10.1002/ejoc.201201309
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridinium chlorochromate / dichloromethane / 4 h / 20 °C
2.1: titanium tetrachloride; titanium(IV) isopropylate; silver(l) oxide; (S)-[1,1']-binaphthalenyl-2,2'-diol / dichloromethane / 48 h / -15 - 0 °C / Inert atmosphere; Darkness
3.1: sodium hydride / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere
3.2: 12 h / 0 - 20 °C
3.3: Inert atmosphere
With
titanium(IV) isopropylate; (S)-[1,1']-binaphthalenyl-2,2'-diol; titanium tetrachloride; sodium hydride; pyridinium chlorochromate; silver(l) oxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/ejoc.201201309
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: titanium tetrachloride; titanium(IV) isopropylate; silver(l) oxide; (S)-[1,1']-binaphthalenyl-2,2'-diol / dichloromethane / 48 h / -15 - 0 °C / Inert atmosphere; Darkness
2.1: sodium hydride / tetrahydrofuran / 0.33 h / 0 °C / Inert atmosphere
2.2: 12 h / 0 - 20 °C
2.3: Inert atmosphere
With
titanium(IV) isopropylate; (S)-[1,1']-binaphthalenyl-2,2'-diol; titanium tetrachloride; sodium hydride; silver(l) oxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/ejoc.201201309
