8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline

Base Information

Chemical Name:8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline
CAS No.:18706-22-4
Molecular Formula:C₁₀H₅ClF₃NO
Molecular Weight:247.604
Hs Code.:2933499090
European Community (EC) Number:671-982-1
DSSTox Substance ID:DTXSID70371476
Nikkaji Number:J1.577.354E
Wikidata:Q70000075
Mol file:18706-22-4.mol

Synonyms:18706-22-4;8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline;8-Chloro-2-(trifluoromethyl)quinolin-4-ol;8-chloro-2-(trifluoromethyl)-1H-quinolin-4-one;MFCD00276589;8-Chloro-2-trifluoromethyl-quinolin-4-ol;8-Chloro-2-(trifluoromethyl)-4-quinolinol;Maybridge1_004966;SCHEMBL2711485;SCHEMBL15491565;HMS555J16;DTXSID70371476;SBVZSZNYPRWWNN-UHFFFAOYSA-N;AC7542;AKOS009157904;AKOS015850463;AC-7364;SB68612;AS-65261;KM 09477;SY005926;CS-0312659;FT-0621524;2-(Trifluoromethyl)-4-hydroxy-8-chloroquinoline;A813107

Suppliers and Price of 8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
500mg
$ 155.00

SynQuest Laboratories
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline 97%
5 g
$ 170.00

SynQuest Laboratories
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline 97%
1 g
$ 39.00

Matrix Scientific
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
1g
$ 24.00

Matrix Scientific
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
5g
$ 74.00

Crysdot
8-Chloro-2-(trifluoromethyl)quinolin-4-ol 97%
100g
$ 543.00

Chemenu
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline 97%
100g
$ 513.00

Biosynth Carbosynth
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
25 g
$ 249.50

Biosynth Carbosynth
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
2 g
$ 60.00

Biosynth Carbosynth
8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline
10 g
$ 155.90

Total 24 raw suppliers

Chemical Property of 8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:0.0173mmHg at 25°C
Melting Point:138 °C
Refractive Index:1.567
Boiling Point:333.882 °C at 760 mmHg
PKA:6.21±0.40(Predicted)
Flash Point:155.726 °C
PSA：33.12000
Density:1.541 g/cm³
LogP:3.61260
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:247.0011760
Heavy Atom Count:16
Complexity:339

Purity/Quality:

97% ^*data from raw suppliers

8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)Cl)NC(=CC2=O)C(F)(F)F

Technology Process of 8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline

There total 1 articles about 8-Chloro-4-Hydroxy-2-(Trifluoromethyl)Quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 95-51-2
o-chloroaniline

: 372-31-6
ethyl 4,4,4-trifluoroacetoacetate

: 1565779-71-6,18706-22-4
C₁₀H₅ClF₃NO

Guidance literature:: ethyl 4,4,4-trifluoroacetoacetate; With polyphosphoric acid; at 100 ℃; for 0.25h;

o-chloroaniline; at 100 - 150 ℃; for 3h;