5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Base Information

Chemical Name:5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol
CAS No.:900509-76-4
Molecular Formula:C₂₅H₃₆O₈
Molecular Weight:464.556
Hs Code.:

Synonyms:5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Suppliers and Price of 5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

There total 11 articles about 5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 900509-75-3
5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pent-1-yn-3-ol

: 900509-76-4
5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Guidance literature:: With hydrogen; potassium carbonate; palladium on activated charcoal; In ethyl acetate; at 20 ℃; for 2h;
DOI:10.1016/j.tet.2006.04.026

Reference yield:

: 90-05-1
2-methoxy-phenol

: 900509-76-4
5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Guidance literature:: Multi-step reaction with 6 steps

1.1: 88 percent / i-Pr₂NEt / CH₂Cl₂ / 0 - 20 °C

2.1: n-BuLi / tetrahydrofuran / 2 h / -15 - 20 °C

2.2: 14 percent / I₂ / tetrahydrofuran / -45 - 20 °C

3.1: 99 percent / Ph₃P; Et₃N; CuI / PdCl₂(PPh₃)2 / 80 °C

4.1: 72 percent / NaOH / toluene / 3.5 h / Heating

5.1: n-BuLi / tetrahydrofuran; hexane / 0.67 h / -78 °C

5.2: 54 percent / tetrahydrofuran; hexane / -78 - 20 °C

6.1: 83 percent / H₂; K₂CO₃ / Pd/C / ethyl acetate / 2 h / 20 °C

With sodium hydroxide; copper(l) iodide; n-butyllithium; hydrogen; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal; In tetrahydrofuran; hexane; dichloromethane; ethyl acetate; toluene; 3.1: Sonogashira coupling;
DOI:10.1016/j.tet.2006.04.026

Reference yield:

: 68945-13-1
1-allyl-3-methoxy-2-((2-methoxyethoxy)methoxy)benzene

: 900509-76-4
5-[3-methoxy-2-((2-methoxyethoxy)methoxy)phenyl]-1-[3-methoxy-2-(methoxymethoxy)phenyl]-pentan-3-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: BH₃*SMe₂ / tetrahydrofuran / 0 - 20 °C

1.2: 55 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran; methanol / 20 °C

2.1: 70 percent / 4 Angstroem molecular sieves; tetra-n-propylammonium perruthenate; 4-methylmorpholine N-oxide / CH₂Cl₂ / 1 h / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.67 h / -78 °C

3.2: 54 percent / tetrahydrofuran; hexane / -78 - 20 °C

4.1: 83 percent / H₂; K₂CO₃ / Pd/C / ethyl acetate / 2 h / 20 °C

With n-butyllithium; tetrapropylammonium perruthennate; dimethylsulfide borane complex; 4 A molecular sieve; hydrogen; potassium carbonate; 4-methylmorpholine N-oxide; palladium on activated charcoal; In tetrahydrofuran; hexane; dichloromethane; ethyl acetate;
DOI:10.1016/j.tet.2006.04.026