phenyl hydrogen methylphosphonate

Base Information

• Chemical Name: phenyl hydrogen methylphosphonate
• CAS No.: 13091-13-9
• Molecular Formula: C₇H₉O₃P
• Molecular Weight: 172.12
• Mol file: 13091-13-9.mol

Synonyms:phenyl hydrogen methylphosphonate

Chemical Property of phenyl hydrogen methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl hydrogen methylphosphonate

There total 8 articles about phenyl hydrogen methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.7%

diphenyl methylphosphonate (7526-26-3) → phenyl hydrogen methylphosphonate (13091-13-9)

Guidance literature:

With water; sodium hydroxide; Reflux;

Reference yield:

4-Hydroxyacetophenone (99-93-4) → phenyl hydrogen methylphosphonate (13091-13-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine

1.2: triethylamine / 20 °C

2.1: bacterial phosphotriesterase I₁₀₆G, F₁₃₂G, S₃₀₈A mutant / various solvent(s) / pH 9.0

With bacterial phosphotriesterase I₁₀₆G; S₃₀₈A mutant; triethylamine; In various solvent(s);

DOI:10.1021/ja0658618

Reference yield:

phenol (108-95-2,27073-41-2) → phenyl hydrogen methylphosphonate (13091-13-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine

1.2: triethylamine / 20 °C

2.1: bacterial phosphotriesterase G₆₀A mutant / various solvent(s) / pH 9.0

With bacterial phosphotriesterase G₆₀A mutant; triethylamine; In various solvent(s);

DOI:10.1021/ja0658618

upstream raw materials:

phenyl methylphosphonochloridate

methylphosphonic acid dichloroanhydride

phenol

4-acetylphenyl methyl phenylphosphonate

Downstream raw materials:

(hydroxy{[(phenoxy)(methyl)phosphoryl]oxy}iodo)benzene