Technology Process of <2-(2,4-dichlorophenoxy)phenyl>acetohydroxamic acid
There total 22 articles about <2-(2,4-dichlorophenoxy)phenyl>acetohydroxamic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide; hydroxylamine hydrochloride;
In
benzene;
Ambient temperature;
DOI:10.1021/jm00364a004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / triethylamine / acetone / 1 h / Heating
2: 82 percent / H2 / 10percent Pd/C / ethyl acetate / 760 Torr
3: 1.) sodium nitrite, concd. H2SO4, 2.) cuprous chloride, concd. HCl / 1.) acetic acid, 0 deg C, 2.) acetic acid, a) from 5 deg C to RT, 1 h, b) 80 deg C, 30 min
4: thionyl chloride / 2 h / 100 °C
5: 68 percent / hydroxylamine hydrochloride, aq. sodium hydroxide / benzene / Ambient temperature
With
hydrogenchloride; sodium hydroxide; thionyl chloride; sulfuric acid; hydroxylamine hydrochloride; hydrogen; triethylamine; copper(l) chloride; sodium nitrite;
palladium on activated charcoal;
In
ethyl acetate; acetone; benzene;
DOI:10.1021/jm00364a004
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 80 percent / triethylamine / acetone / 1 h / Heating
2: 82 percent / H2 / 10percent Pd/C / ethyl acetate / 760 Torr
3: 1.) sodium nitrite, concd. H2SO4, 2.) cuprous chloride, concd. HCl / 1.) acetic acid, 0 deg C, 2.) acetic acid, a) from 5 deg C to RT, 1 h, b) 80 deg C, 30 min
4: thionyl chloride / 2 h / 100 °C
5: 68 percent / hydroxylamine hydrochloride, aq. sodium hydroxide / benzene / Ambient temperature
With
hydrogenchloride; sodium hydroxide; thionyl chloride; sulfuric acid; hydroxylamine hydrochloride; hydrogen; triethylamine; copper(l) chloride; sodium nitrite;
palladium on activated charcoal;
In
ethyl acetate; acetone; benzene;
DOI:10.1021/jm00364a004
