5-iodo-2'-deoxycytidine monophosphate

Base Information

• Chemical Name: 5-iodo-2'-deoxycytidine monophosphate
• CAS No.: 1379798-18-1
• Molecular Formula: C₉H₁₂IN₃O₇P*Na
• Molecular Weight: 455.078
• Mol file: 1379798-18-1.mol

Synonyms:5-iodo-2'-deoxycytidine monophosphate

Chemical Property of 5-iodo-2'-deoxycytidine monophosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-iodo-2'-deoxycytidine monophosphate

There total 1 articles about 5-iodo-2'-deoxycytidine monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

5-Iodo-2'-deoxycytidine (611-53-0) → 5-iodo-2'-deoxycytidine monophosphate (1379798-18-1)

Guidance literature:

5-Iodo-2'-deoxycytidine; With trimethyl phosphite; trichlorophosphate; at 0 - 80 ℃; for 6h; Inert atmosphere;

In water; Inert atmosphere;

DOI:10.1002/chem.201103270

Reference yield: 80.0%

5-iodo-2'-deoxycytidine monophosphate (1379798-18-1) + 4-formylphenylboronic acid, (87199-17-5) → C16H17N3O8P(1-)*Na(1+) (1379798-20-5)

Guidance literature:

5-iodo-2'-deoxycytidine monophosphate; 4-formylphenylboronic acid,; With trisodium tris(3-sulfophenyl)phosphine; palladium diacetate; caesium carbonate; In water; acetonitrile; at 90 ℃; for 2h; Inert atmosphere;

In water; Inert atmosphere;

DOI:10.1002/chem.201103270

Reference yield: 75.0%

(2-fluoro-5-formylphenyl)boronic acid (352534-79-3) + 5-iodo-2'-deoxycytidine monophosphate (1379798-18-1) → C16H16FN3O8P(1-)*Na(1+) (1379798-21-6)

Guidance literature:

(2-fluoro-5-formylphenyl)boronic acid; 5-iodo-2'-deoxycytidine monophosphate; With trisodium tris(3-sulfophenyl)phosphine; palladium diacetate; caesium carbonate; In water; acetonitrile; at 75 ℃; for 1.5h; Inert atmosphere;

In water; Inert atmosphere;

DOI:10.1002/chem.201103270

upstream raw materials:

5-Iodo-2'-deoxycytidine

Downstream raw materials:

C₁₆H₁₆FN₃O₈P^(1-)*Na⁽¹⁺⁾

C₁₆H₁₉N₃O₈P^(1-)*Na⁽¹⁺⁾

C₁₆H₁₈FN₃O₈P^(1-)*Na⁽¹⁺⁾

C₂₄H₃₃FN₆O₉P^(1-)*Na⁽¹⁺⁾