4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

Base Information

Chemical Name:4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide
CAS No.:139209-26-0
Molecular Formula:C₁₃H₁₇N₅O₅
Molecular Weight:323.308
Hs Code.:
Mol file:139209-26-0.mol

Synonyms:4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

Suppliers and Price of 4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

Chemical Property:

PSA：169.74000
LogP:-0.60450

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide

There total 10 articles about 4-Amino-7-(2-C-methyl-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19393-83-0
4-amino-6-bromo-5-cyanopyrrolo[2,3-d]pyrimidine

: 139209-26-0
2'-C-methylsangivamycin

Guidance literature:: Multi-step reaction with 4 steps

1: 84 percent / N,N-dimethylaminopyridine (DMAP), pyridine / 36 h / 90 °C

2: 76 percent / conc. NH₄OH, H₂ / 10percent Pd/C / ethanol / 27 h / 25 °C / 760 Torr

3: 1.) NaH, molecular sieves 4A, 3.) TFA

4: 35percent aq. H₂O₂, conc. NH₄OH / 1 h / Ambient temperature

With pyridine; dmap; ammonium hydroxide; 4 A molecular sieve; hydrogen; dihydrogen peroxide; sodium hydride; trifluoroacetic acid; palladium on activated charcoal; In ethanol;

Reference yield:

: 141232-17-9
6-bromo-5-cyano-4-tritylaminopyrrolo<2,3-d>pyrimidine

: 139209-26-0
2'-C-methylsangivamycin

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / conc. NH₄OH, H₂ / 10percent Pd/C / ethanol / 27 h / 25 °C / 760 Torr

2: 1.) NaH, molecular sieves 4A, 3.) TFA

3: 35percent aq. H₂O₂, conc. NH₄OH / 1 h / Ambient temperature

With ammonium hydroxide; 4 A molecular sieve; hydrogen; dihydrogen peroxide; sodium hydride; trifluoroacetic acid; palladium on activated charcoal; In ethanol;

Reference yield:

: 943638-31-1
2,3-O-isopropylidene-1-hydroxy-2-C-methyl-5-O-trityl-D-ribofuranose

: 139209-26-0
2'-C-methylsangivamycin

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / (Me₂N)3P, CCl₄ / diethyl ether / 0 °C

2: 1.) NaH, molecular sieves 4A, 3.) TFA

3: 35percent aq. H₂O₂, conc. NH₄OH / 1 h / Ambient temperature

With tetrachloromethane; ammonium hydroxide; 4 A molecular sieve; dihydrogen peroxide; sodium hydride; trifluoroacetic acid; Hexamethylphosphorous triamide; In diethyl ether;