tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate

Base Information

Chemical Name:tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate
CAS No.:1273585-66-2
Molecular Formula:C₁₄H₁₈ClNO₄
Molecular Weight:299.754
Hs Code.:
Mol file:1273585-66-2.mol

Synonyms:methyl 2-(tert-butoxycarbonylamino)-2-(4-chlorophenyl)acetate

Suppliers and Price of tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl2-((tert-butoxycarbonyl)amino)-2-(4-chlorophenyl)acetate 95+%
1g
$ 491.00

Chemenu
Methyl2-((tert-butoxycarbonyl)amino)-2-(4-chlorophenyl)acetate 95%
1g
$ 464.00

Alichem
Methyl2-((tert-butoxycarbonyl)amino)-2-(4-chlorophenyl)acetate
1g
$ 429.07

Acrotein
Methyl2-((tert-butoxycarbonyl)amino)-2-(4-chlorophenyl)acetate 97%
0.5g
$ 320.79

Total 9 raw suppliers

Chemical Property of tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate

Chemical Property:

Boiling Point:413.6±40.0 °C(Predicted)
PKA:10.53±0.46(Predicted)
Density:1.199±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-((tert-butoxycarbonyl)amino)-2-(4-chlorophenyl)acetate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate

There total 9 articles about tert-butyl (Methoxycarbonyl)(4-chlorophenyl)MethylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 124-38-9,18923-20-1
carbon dioxide

: 774225-25-1
N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-chlorobenzylamine

: 1273585-66-2
methyl 2-(tert-butoxycarbonylamino)-2-(4-chlorophenyl)acetate

Guidance literature:: carbon dioxide; N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-chlorobenzylamine; With toluene-4-sulfonic acid; cesium fluoride; dimethylphenyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane; In N,N-dimethyl-formamide; at 20 ℃; for 3h; under 3750.38 Torr;

diazomethane; In diethyl ether;
DOI:10.1021/ol302952r

Reference yield: 64.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 124-38-9,18923-20-1
carbon dioxide

: 774225-25-1
N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-chlorobenzylamine

: 1273585-66-2
methyl 2-(tert-butoxycarbonylamino)-2-(4-chlorophenyl)acetate

: 120157-95-1
(4-chlorobenzyl)carbamic acid tert-butyl ester

Guidance literature:: carbon dioxide; N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-4-chlorobenzylamine; With trimethylsilyltributyltin; cesium fluoride; In N,N-dimethyl-formamide; at 100 ℃; for 3h; under 7500.75 Torr;

diazomethane; In diethyl ether;
DOI:10.1021/ol302952r

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 1291065-80-9
C₂₄H₄₂ClNO₂Sn

: 18107-18-1
diazomethyl-trimethyl-silane

: 1273585-66-2
methyl 2-(tert-butoxycarbonylamino)-2-(4-chlorophenyl)acetate

: 120157-95-1
(4-chlorobenzyl)carbamic acid tert-butyl ester

Guidance literature:: carbon dioxide; C₂₄H₄₂ClNO₂Sn; With cesium fluoride; In N,N-dimethyl-formamide; at 100 ℃; for 3h; under 7500.75 Torr; Autoclave;

With hydrogenchloride; In diethyl ether; water; N,N-dimethyl-formamide; at 0 ℃; pH=2; Inert atmosphere;

diazomethyl-trimethyl-silane; In methanol; diethyl ether; for 1h; Inert atmosphere;
DOI:10.1021/jo202597p