5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone

Base Information

Chemical Name:5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone
CAS No.:908128-94-9
Molecular Formula:C₁₀H₁₆O₇S
Molecular Weight:280.299
Hs Code.:
Mol file:908128-94-9.mol

Synonyms:5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone;5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-γ-lactone;5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-Methyl-D-ribonic-gMMa-lactone

Suppliers and Price of 5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone

Chemical Property:

PSA：96.51000
Density:1.330
LogP:0.87900

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone

There total 2 articles about 5-O-Methanesulfonate-2,3-O-isopropylidene-2-C-methyl-D-ribonic-gamma-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 23709-41-3
2-methyl-2,3-O-(1-methylethylidene)-D-ribonic acid γ-lactone

: 124-63-0
methanesulfonyl chloride

: 908128-94-9
2,3-O-isopropylidene-5-O-methanesulfonyl-2-C-methyl-D-ribono-1,4-lactone

Guidance literature:: With dmap; In pyridine;
DOI:10.1016/j.tetlet.2006.11.137

Reference yield:

: 492-30-8,7306-56-1,19774-08-4,36791-96-5,36791-97-6,53008-90-5,53008-96-1,53008-97-2,86204-17-3,86204-18-4,93636-22-7
2-C-methyl-D-ribono-1,4-lactone

: 908128-94-9
2,3-O-isopropylidene-5-O-methanesulfonyl-2-C-methyl-D-ribono-1,4-lactone

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂SO₄

2: pyridine / CH₂Cl₂

With pyridine; sulfuric acid; In dichloromethane;
DOI:10.1081/NCN-200061823

Reference yield:

: 908128-94-9
2,3-O-isopropylidene-5-O-methanesulfonyl-2-C-methyl-D-ribono-1,4-lactone

: C₆H₁₁O₃S(NCHCHCNH(COC₆H₅)NCO)

Guidance literature:: Multi-step reaction with 10 steps

1: 55 percent / aq. KOH

2: pyridine / CH₂Cl₂

3: methanol

4: 37 percent / thiourea / methanol

5: 60 percent / acetic acid; AcONa

6: NaBH₄ / methanol

7: pyridine

8: aq. acetic acid

9: pyridine

10: 35 percent / bis(trimethylsilyl)acetamide; TMSOTf / acetonitrile / Heating

With pyridine; potassium hydroxide; sodium tetrahydroborate; trimethylsilyl trifluoromethanesulfonate; sodium acetate; acetic acid; bis-(trimethylsilyl)acetamide; thiourea; In methanol; dichloromethane; acetonitrile;
DOI:10.1081/NCN-200061823