methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate

Base Information

• Chemical Name: methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate
• CAS No.: 1222181-60-3
• Molecular Formula: C₂₀H₁₉BrO₆
• Molecular Weight: 435.271
• Mol file: 1222181-60-3.mol

Synonyms:methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate

Chemical Property of methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate

There total 1 articles about methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methyl 4-fluorobenzenesulfonate (1222181-59-0) + methoxymethyl 4-hydroxybenzoate → methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate (1222181-60-3)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; at 70 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.01.030

Reference yield: 41.0%

methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate (1222181-60-3) → methoxymethyl 4-{[4-(4-bromophenyl)-5-oxo-2,5-dihydrofuran-2-yl]methoxy}benzoate (1222181-67-0)

Guidance literature:

methoxymethyl 4-{[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methoxy}benzoate; With lithium diisopropyl amide; In tetrahydrofuran; cyclohexane; at -70 ℃; Inert atmosphere;

With Phenylselenyl bromide; In tetrahydrofuran; cyclohexane; at -70 - 20 ℃; Inert atmosphere;

With dihydrogen peroxide; sodium hydrogencarbonate; In tetrahydrofuran; water; ethyl acetate; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2010.01.030

upstream raw materials:

[4-(4-bromophenyl)-5-oxotetrahydrofuran-2-yl]methyl 4-fluorobenzenesulfonate

Downstream raw materials:

methoxymethyl 4-{[4-(4-bromophenyl)-5-oxo-2,5-dihydrofuran-2-yl]methoxy}benzoate