5-Amino-2-methylpyrimidine-4,6-diol

Base Information

• Chemical Name: 5-Amino-2-methylpyrimidine-4,6-diol
• CAS No.: 98797-08-1
• Molecular Formula: C5H7 N3 O2
• Molecular Weight: 141.129
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID301251588
• Mol file: 98797-08-1.mol

Synonyms:5-amino-2-methylpyrimidine-4,6-diol;98797-08-1;5-amino-4-hydroxy-2-methyl-1H-pyrimidin-6-one;5-amino-4,6-dihydroxy-2-methylpyrimidine;4(3H)-Pyrimidinone,5-amino-6-hydroxy-2-methyl-;SCHEMBL4734595;YICLTNFWMVEECR-UHFFFAOYSA-N;DTXSID301251588;AKOS000297950;AKOS000298917;SB56777;VS-03453;5-Amino-6-hydroxy-2-methyl-4(3H)-pyrimidinone

Chemical Property of 5-Amino-2-methylpyrimidine-4,6-diol

Chemical Property:

• PSA: 92.26000
• LogP: 0.35960
• XLogP3: -1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 141.053826475
• Heavy Atom Count: 10
• Complexity: 241

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-amino-2-methylpyrimidine-4,6-diol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=C(C(=O)N1)N)O

Technology Process of 5-Amino-2-methylpyrimidine-4,6-diol

There total 1 articles about 5-Amino-2-methylpyrimidine-4,6-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4,6-dihydroxy-2-methylpyrimidin-5-yl)acetamide (98797-16-1) → 5-amino-4,6-dihydroxy-2-methylpyrimidine (98797-08-1)

Guidance literature:

With hydrogenchloride; In methanol; water; at 20 - 50 ℃; for 15.5h; Inert atmosphere;

Reference yield: 53.0%

acetic anhydride (108-24-7) + 5-amino-4,6-dihydroxy-2-methylpyrimidine (98797-08-1) → 2,5-dimethyloxazolo[5,4-d]pyrimidin-7-ol (959238-51-8)

Guidance literature:

at 120 ℃;

Reference yield: 26.0%

5-amino-4,6-dihydroxy-2-methylpyrimidine (98797-08-1) → 5-amino-4,6-dichloro-2-methylpyrimidine (39906-04-2)

Guidance literature:

With trichlorophosphate; at 110 ℃; for 20h; Inert atmosphere; Sealed tube;

upstream raw materials:

N-(4,6-dihydroxy-2-methylpyrimidin-5-yl)acetamide

Downstream raw materials:

2,5-dimethyloxazolo[5,4-d]pyrimidin-7-ol

5-amino-4,6-dichloro-2-methylpyrimidine