C₃₃H₂₆BrN₃O₆S

Base Information

• Chemical Name: C₃₃H₂₆BrN₃O₆S
• CAS No.: 1315476-18-6
• Molecular Formula: C₃₃H₂₆BrN₃O₆S
• Molecular Weight: 672.556
• Mol file: 1315476-18-6.mol

Synonyms:C₃₃H₂₆BrN₃O₆S

Chemical Property of C₃₃H₂₆BrN₃O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₂₆BrN₃O₆S

There total 19 articles about C₃₃H₂₆BrN₃O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

benzoyl chloride (98-88-4) + (+)-5-(toluene-4-sulfonyl)-3,5,7,8,9,10-hexahydro-2H-triazaacephenanthrylen-6-one-8-(hydroxymethyl)-10-spiro-4'-(2'-bromo)cyclohexa-2',5'-dien-1'-one (590385-73-2) → C33H26BrN3O6S (1315476-18-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c1ob05058c

Reference yield:

2-nitroveratraldehyde (55149-84-3) → C33H26BrN3O6S (1315476-18-6)

Guidance literature:

Multi-step reaction with 11 steps

1: potassium hydroxide / ethanol; N,N-dimethyl-formamide / 1.25 h / -2 °C

2: palladium on carbon; formic acid; ammonium formate / methanol / 1 h

3: 2 h / 0 °C

4: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / Reflux

5: diphenyl phosphoryl azide; triphenylphosphine; diethylazodicarboxylate / toluene / 9 h

6: potassium tert-butylate / tetrahydrofuran / 6 h / 0 °C

7: 1,1,1,3',3',3'-hexafluoro-propanol; trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene / water / 1 h / 0 °C

8: hydrogenchloride / methanol / 36 h / 20 °C

9: bis-[(trifluoroacetoxy)iodo]benzene / 2,2,2-trifluoroethanol / 7 h / 20 °C

10: boron trifluoride diethyl etherate / dichloromethane / 7 h / 0 - 20 °C

11: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; lithium aluminium tetrahydride; formic acid; 1,1,1,3',3',3'-hexafluoro-propanol; trimethylsilyl trifluoromethanesulfonate; diphenyl phosphoryl azide; palladium on carbon; boron trifluoride diethyl etherate; potassium tert-butylate; ammonium formate; triethylamine; triphenylphosphine; bis-[(trifluoroacetoxy)iodo]benzene; potassium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; ethanol; dichloromethane; 2,2,2-trifluoroethanol; water; N,N-dimethyl-formamide; toluene; 5: Mitsunobu reaction;

DOI:10.1039/c1ob05058c

Reference yield:

6,7-dimethoxy-1H-indole (31165-13-6) → C33H26BrN3O6S (1315476-18-6)

Guidance literature:

Multi-step reaction with 9 steps

1: 2 h / 0 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 2.5 h / Reflux

3: diphenyl phosphoryl azide; triphenylphosphine; diethylazodicarboxylate / toluene / 9 h

4: potassium tert-butylate / tetrahydrofuran / 6 h / 0 °C

5: 1,1,1,3',3',3'-hexafluoro-propanol; trimethylsilyl trifluoromethanesulfonate; bis-[(trifluoroacetoxy)iodo]benzene / water / 1 h / 0 °C

6: hydrogenchloride / methanol / 36 h / 20 °C

7: bis-[(trifluoroacetoxy)iodo]benzene / 2,2,2-trifluoroethanol / 7 h / 20 °C

8: boron trifluoride diethyl etherate / dichloromethane / 7 h / 0 - 20 °C

9: triethylamine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; lithium aluminium tetrahydride; 1,1,1,3',3',3'-hexafluoro-propanol; trimethylsilyl trifluoromethanesulfonate; diphenyl phosphoryl azide; boron trifluoride diethyl etherate; potassium tert-butylate; triethylamine; triphenylphosphine; bis-[(trifluoroacetoxy)iodo]benzene; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; 2,2,2-trifluoroethanol; water; toluene; 3: Mitsunobu reaction;

DOI:10.1039/c1ob05058c

upstream raw materials:

6,7-dimethoxy-1H-indole

2-nitroveratraldehyde

L-tyrosine methyl ester HCl

benzoyl chloride