S-glutathione

Base Information

• Chemical Name: S-glutathione
• CAS No.: 156727-61-6
• Molecular Formula: C₁₇H₂₁ClN₄O₈S
• Molecular Weight: 476.895

Synonyms:S-glutathione

Chemical Property of S-glutathione

Chemical Property:

Purity/Quality:

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Technology Process of S-glutathione

There total 4 articles about S-glutathione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

GLUTATHIONE (70-18-8) + N-hydroxy-N-(-4-chlorophenyl)carbamate 4-chlorophenyl ester (13649-22-4) → S-glutathione (156727-61-6)

Guidance literature:

In ethanol; water; for 27h; Ambient temperature;

DOI:10.1021/jm00040a007

Reference yield:

GLUTATHIONE (70-18-8) + N-(4-Chlor-phenyl)-N-ethylmercaptocarbonyl-hydroxylamin (14063-23-1) → S-glutathione (156727-61-6) + ethanethiol (75-08-1)

Guidance literature:

With potassium phosphate buffer; ethanol; at 25 ℃; Rate constant;

DOI:10.1021/jm980712o

Reference yield:

N-(4-chlorophenyl)hydroxylamine (823-86-9) → S-glutathione (156727-61-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / K₂CO₃ / diethyl ether; H₂O / 1.5 h / 0 - 20 °C

2: 34 percent / ethanol; H₂O / 27 h / Ambient temperature

With potassium carbonate; In diethyl ether; ethanol; water;

DOI:10.1021/jm00040a007

upstream raw materials:

GLUTATHIONE

N-hydroxy-N-(-4-chlorophenyl)carbamate 4-chlorophenyl ester

N-(4-Chlor-phenyl)-N-ethylmercaptocarbonyl-hydroxylamin

S-(N-4-chlorophenyl-N-hydroxycarbamoyl) ethyl sulfoxide

Downstream raw materials:

C₃₈H₅₆ClN₁₁O₁₅S

C₃₅H₅₁ClN₁₀O₁₄S

C₃₂H₄₆ClN₉O₁₃S

C₂₉H₄₁ClN₈O₁₂S

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