Ethanethiol

Base Information

• Chemical Name: Ethanethiol
• CAS No.: 75-08-1
• Molecular Formula: C2H6S
• Molecular Weight: 62.1356
• European Community (EC) Number: 200-837-3
• ICSC Number: 0470
• NSC Number: 93877
• UN Number: 2363
• UNII: M439R54A1D
• DSSTox Substance ID: DTXSID9026394
• Nikkaji Number: J1.439G
• Wikipedia: Ethanethiol
• Wikidata: Q407918
• Mol file: 75-08-1.mol

Synonyms:ethanethiol;ethanethiol silver salt (+2);ethanethiol sodium salt;ethyl mercaptan

Chemical Property of Ethanethiol

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 537mmHg at 25°C
• Melting Point: -148 °C
• Refractive Index: 1.4864
• Boiling Point: 34.663 °C at 760 mmHg
• Flash Point: 1 °F
• PSA: 38.80000
• Density: 0.822 g/cm³
• LogP: 0.93610
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 62.01902136
• Heavy Atom Count: 3
• Complexity: 2.8
• Transport DOT Label: Flammable Liquid

Purity/Quality:

99.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F; Xn;N
• Hazard Codes: F:Flammable;;
• Statements: R11:; R20:; R50/53:
• Safety Statements: S16:; S25:; S60:; S61:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Thiols
• Canonical SMILES: CCS
• Inhalation Risk: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system. This may result in lowering of consciousness and respiratory depression.

Technology Process of Ethanethiol

There total 439 articles about Ethanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-ethyl 4-methoxybenzothioate (22872-52-2) → 4-methoxybenzoic acid (100-09-4) + ethanethiol (75-08-1)

Guidance literature:

With sulfuric acid; In water; at 25 ℃; Mechanism;

DOI:10.1139/v82-438

Reference yield:

1-Ethylsulfanyl-4-(4-nitro-phenylazo)-isoquinolin-3-ol (109541-34-6) → 4-aminohomophthalimide (804430-99-7) + 4-nitro-aniline (100-01-6,104810-17-5) + ethanethiol (75-08-1)

Guidance literature:

In ethanol; water; at 20 ℃; controlled potential electrolysis;

Reference yield:

benzaldehyde diethyldithioacetal (7334-52-3) → benzaldehyde (100-52-7) + ethanethiol (75-08-1)

Guidance literature:

With perchloric acid; In 1,4-dioxane; water; at 25 ℃; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.);

upstream raw materials:

1-Ethylsulfanyl-4-p-tolylazo-isoquinolin-3-ol

4-(4-Chloro-phenylazo)-1-ethylsulfanyl-isoquinolin-3-ol

1-Ethylsulfanyl-4-(4-methoxy-phenylazo)-isoquinolin-3-ol

5,6-dihydro-2,4,6-trimethyl-4H-1,3,5-dithiazine

Downstream raw materials:

2-(ethylsulfanyl)ethanol

ethyl-trisulfane

2-(2-ethylsulfanyl-ethylsulfanyl)-ethanethiol

2-ethylsulfanyl-ethanethiol

Refernces

• 1、 Brown,Snyder. "-". . p. 1927. Retrieved 1926.
• 2、 Gore, Sangram,Ukhanov, Kirill,Herbivo, Cyril,Asad, Naeem,Bobkov, Yuriy V.,Martens, Jeffrey R.,Dore, Timothy M.. "Photoactivatable Odorants for Chemosensory Research". . p. 2516 - 2528. Retrieved 2020/10/02.
• 3、 Ma, Ming,Lohman, Jeremy R.,Liu, Tao,Shen, Ben. "C-S bond cleavage by a polyketide synthase domain". . p. 10359 - 10364. Retrieved 2015/09/01.