2-Bromo-4-fluorobenzylamine hydrochloride

Base Information

Chemical Name:2-Bromo-4-fluorobenzylamine hydrochloride
CAS No.:289038-14-8
Molecular Formula:C₇H₇BrFN*ClH
Molecular Weight:240.503
Hs Code.:2921490090
European Community (EC) Number:608-273-3
DSSTox Substance ID:DTXSID30378401
Mol file:289038-14-8.mol

Synonyms:289038-14-8;2-Bromo-4-fluorobenzylamine hydrochloride;(2-bromo-4-fluorophenyl)methanamine hydrochloride;2-Bromo-4-fluorobenzylamine, HCl;(2-bromo-4-fluorophenyl)methanamine;hydrochloride;(2-Bromo-4-fluorophenyl)methanamine HCl;Benzenemethanamine, 2-bromo-4-fluoro-, hydrochloride (1:1);SCHEMBL856646;2-Bromo-4-fluorobenzylamine HCl;DTXSID30378401;MFCD00672922;AKOS026675589;PS-7584;CS-0156854;EN300-156065;Y11612;(2-bromo-4-fluorophenyl)methanaminehydrochloride;A819659;A1-00615;Z2238930616

Suppliers and Price of 2-Bromo-4-fluorobenzylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-4-fluorobenzylaminehydrochloride
500mg
$ 90.00

SynQuest Laboratories
2-Bromo-4-fluorobenzylamine hydrochloride
1 g
$ 77.00

SynQuest Laboratories
2-Bromo-4-fluorobenzylamine hydrochloride
5 g
$ 256.00

Matrix Scientific
(2-Bromo-4-fluorophenyl)methanaminehydrochloride
5g
$ 800.00

Matrix Scientific
(2-Bromo-4-fluorophenyl)methanaminehydrochloride
25g
$ 2240.00

Labseeker
2-Bromo-4-Fluorobenzylamine Hydrochloride 95
50g
$ 2200.00

Labseeker
2-Bromo-4-Fluorobenzylamine Hydrochloride 95
25g
$ 1600.00

Labseeker
2-Bromo-4-Fluorobenzylamine Hydrochloride 95
100g
$ 3483.00

Crysdot
(2-Bromo-4-fluorophenyl)methanaminehydrochloride 97%
5g
$ 447.00

Apolloscientific
2-Bromo-4-fluorobenzylaminehydrochloride
1g
$ 40.00

Total 13 raw suppliers

Chemical Property of 2-Bromo-4-fluorobenzylamine hydrochloride

Chemical Property:

Vapor Pressure:0.0305mmHg at 25°C
Melting Point:251 °C(Solv: ethyl ether (60-29-7))
Storage Temp.:Inert atmosphere,Room Temperature
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:238.95127
Heavy Atom Count:11
Complexity:110

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-4-fluorobenzylaminehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)Br)CN.Cl
Uses 2-Bromo-4-fluorobenzylamine hydrochloride used as a intermediate in pharmaceutical.

Technology Process of 2-Bromo-4-fluorobenzylamine hydrochloride

There total 4 articles about 2-Bromo-4-fluorobenzylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 36282-26-5
2-bromo-4-fluorobenzonitrile

: 289038-14-8
2-bromo-4-fluorobenzylamine hydrochloride

Guidance literature:: With aluminum (III) chloride; lithium aluminium tetrahydride; In diethyl ether; at 0 - 40 ℃; Inert atmosphere;
DOI:10.1039/c0ob00449a

Reference yield:

: 530141-41-4
2-[(2-bromo-4-fluorophenyl)methyl]-1H-isoindole-1,3(2H)-dione

: 289038-14-8
2-bromo-4-fluorobenzylamine hydrochloride

Guidance literature:: 2-[(2-bromo-4-fluorophenyl)methyl]-1H-isoindole-1,3(2H)-dione; With hydrazine; In ethanol; at 20 - 100 ℃;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 1006-41-3
2-bromo-4-fluorobenzoic acid

: 289038-14-8
2-bromo-4-fluorobenzylamine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / 3 h / Reflux; Inert atmosphere

1.2: 16 h / 20 °C

2.1: thionyl chloride / 3 h / Reflux; Inert atmosphere

3.1: lithium aluminium tetrahydride; aluminum (III) chloride / diethyl ether / 0 - 40 °C / Inert atmosphere

With aluminum (III) chloride; lithium aluminium tetrahydride; thionyl chloride; In diethyl ether;
DOI:10.1039/c0ob00449a