4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester

Base Information

• Chemical Name: 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester
• CAS No.: 1333328-04-3
• Molecular Formula: C₃₃H₂₆N₂O₂
• Molecular Weight: 482.582
• Mol file: 1333328-04-3.mol

Synonyms:4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester

Chemical Property of 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester

There total 2 articles about 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-diphenylamino-2'-nitro-[1,1';4',1'']terphenyl-4''-carboxylic acid ethyl ester (1333328-03-2) → 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester (1333328-04-3)

Guidance literature:

With triphenylphosphine; In 1,2-dichloro-benzene; at 160 ℃; for 20h; Inert atmosphere;

DOI:10.1002/anie.201102552

Reference yield:

diphenylamine (122-39-4) → 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester (1333328-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tri-tert-butyl phosphine; palladium diacetate; sodium t-butanolate / toluene / 10 h / 100 °C / Inert atmosphere

2: triphenylphosphine / 1,2-dichloro-benzene / 20 h / 160 °C / Inert atmosphere

With tri-tert-butyl phosphine; palladium diacetate; triphenylphosphine; sodium t-butanolate; In 1,2-dichloro-benzene; toluene;

DOI:10.1002/anie.201102552

Reference yield: 92.0%

1-iodo-butane (542-69-8) + 4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester (1333328-04-3) → 4-(9-butyl-7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester (1355076-63-9)

Guidance literature:

4-(7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h;

1-iodo-butane; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;

DOI:10.1002/anie.201102552

upstream raw materials:

4-diphenylamino-2'-nitro-[1,1';4',1'']terphenyl-4''-carboxylic acid ethyl ester

diphenylamine

Downstream raw materials:

4-(9-butyl-7-diphenylamino-9H-carbazol-2-yl)-benzoic acid

4-(9-butyl-7-diphenylamino-9H-carbazol-2-yl)-benzoic acid

4-(9-butyl-7-diphenylamino-9H-carbazol-2-yl)-benzoic acid ethyl ester