3-Fluoro-4-methylphenol

Base Information

Chemical Name:3-Fluoro-4-methylphenol
CAS No.:452-78-8
Molecular Formula:C7H7FO
Molecular Weight:126.13
Hs Code.:29081990
DSSTox Substance ID:DTXSID60379128
Wikidata:Q72474725
Mol file:452-78-8.mol

Synonyms:3-Fluoro-4-methylphenol;452-78-8;3-Fluoro-p-cresol;3-Fluoro-4-methyl-phenol;Phenol, 3-fluoro-4-methyl-;MFCD00143164;2-Fluoro-4-hydroxytoluene;3-fluoro-4-methyl phenol;3-fluoranyl-4-methyl-phenol;SCHEMBL257925;DTXSID60379128;GJOOCAXPERKNMN-UHFFFAOYSA-N;CL8489;3-Fluoro-4-methylphenol, AldrichCPR;3-Pentanol, 3-methyl-, 3-benzoate;AKOS005063850;AC-3800;CS-W016564;PS-9184;SY019309;A7142;AM20050177;F0481;FT-0615696;EN300-188121;A826757;J-512498

Suppliers and Price of 3-Fluoro-4-methylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Fluoro-4-methylphenol
1g
$ 75.00

TRC
3-Fluoro-4-methylphenol
100mg
$ 45.00

TCI Chemical
3-Fluoro-p-cresol >98.0%(GC)
5g
$ 89.00

TCI Chemical
3-Fluoro-p-cresol >98.0%(GC)
1g
$ 22.00

SynQuest Laboratories
3-Fluoro-4-methylphenol 97%
1 g
$ 50.00

SynQuest Laboratories
3-Fluoro-4-methylphenol 97%
5 g
$ 149.00

Matrix Scientific
3-Fluoro-4-methylphenol 95+%
5g
$ 97.00

Matrix Scientific
3-Fluoro-4-methylphenol 95+%
25g
$ 247.00

Crysdot
3-Fluoro-4-methylphenol 97+%
100g
$ 277.00

Chemenu
3-fluoro-4-methylphenol 97%
100g
$ 225.00

Total 67 raw suppliers

Chemical Property of 3-Fluoro-4-methylphenol

Chemical Property:

Vapor Pressure:0.32mmHg at 25°C
Melting Point:72 °C
Refractive Index:1.52
Boiling Point:194.2 °C at 760 mmHg
PKA:9.27±0.18(Predicted)
Flash Point:83.6 °C
PSA：20.23000
Density:1.164 g/cm³
LogP:1.83970
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:126.048093005
Heavy Atom Count:9
Complexity:94.9

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoro-4-methylphenol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 21/22-34-52-36-22
Safety Statements: 26-36/37/39-60-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)O)F
Uses 3-FLUORO-4-METHYLPHENOL is a phenolic derivative and can be used as a pharmaceutical intermediate.

Technology Process of 3-Fluoro-4-methylphenol

There total 4 articles about 3-Fluoro-4-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 405-06-1
2-fluoro-4-methoxy-1-methylbenzene

: 331746-01-1
3-fluoro-4-methylphenyl carbonochloridate

: 452-78-8
3-fluoro-4-methyl phenol

Guidance literature:: With boron tribromide; In dichloromethane;

Reference yield: 44.8%

: 452-77-7
3-fluoro-4-methyl-phenylamine

: 452-78-8
3-fluoro-4-methyl phenol

Guidance literature:: With sodium nitrate; sulfuric acid; water; at 0 - 80 ℃; for 6h;

Reference yield:

: 1427-07-2
2-fluoro-4-nitrotoluene

: 452-78-8
3-fluoro-4-methyl phenol

Guidance literature:: Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

2: aqueous H₂SO₄; NaNO₂ / anschliessendes Erhitzen

With ethanol; sulfuric acid; platinum; sodium nitrite;
DOI:10.1021/ja01160a113